GO_0042596 | fear response | OmnibusX

fear response

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	ADRA2A	pericyte	4 studies
Group 2	DRD4	retinal cone cell retinal rod cell rod bipolar cell retinal bipolar neuron	8 studies
Group 3	ADRB1	epithelial cell endothelial cell neuron	9 studies
Group 4	EXT1	connective tissue cell neuron epithelial cell endothelial cell glial cell myeloid cell	75 studies

II. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	DBH+SLC18A1-ADRA2A	- ADA2A_HUMAN	Ligand-Receptor	Signaling by Noradrenaline
2	DBH+SLC18A1-ADRB1	- ADRB1_HUMAN	Ligand-Receptor	Signaling by Noradrenaline
3	DBH+SLC18A2-ADRA2A	- ADA2A_HUMAN	Ligand-Receptor	Signaling by Noradrenaline
4	DBH+SLC18A2-ADRB1	- ADRB1_HUMAN	Ligand-Receptor	Signaling by Noradrenaline
5	DBH+SLC6A2-ADRA2A	- ADA2A_HUMAN	Ligand-Receptor	Signaling by Noradrenaline
6	DBH+SLC6A2-ADRB1	- ADRB1_HUMAN	Ligand-Receptor	Signaling by Noradrenaline

III. Literature review

Name	fear response
ID	GO_0042596
collection_id	Biological process
Alternative ID	GO:0001663
Exact synonym	physiological fear response
Description	The response of an organism to a perceived external threat.
External URL
Genes	EXT1 CRHR1 DBH ADRB1 DRD4 ADRA2A