Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | EREG-ERBB4 | EREG_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Epidermal growth factor |
| 2 | HBEGF-ERBB2 | HBEGF_HUMAN - ERBB2_HUMAN | Ligand-Receptor | Signaling by Epidermal growth factor |
| 3 | HBEGF-ERBB4 | HBEGF_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Epidermal growth factor |
| 4 | NRG1-ERBB4 | NRG1_HUMAN - ERBB4_HUMAN | Ligand-Receptor | Signaling by Neuregulin |
| Name | ERBB2-ERBB4 signaling pathway |
| ID | GO_0038135 |
| collection_id | Biological process |
| Exact synonym | ERBB2-ERBB4 signalling pathway, HER2-HER4 signaling pathway |
| Description | The series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4. |
| External URL | |
| Genes |