vascular endothelial growth factor receptor-2 signaling pathway

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1VEGFA-FLT1+KDRVEGFA_HUMAN - Ligand-ReceptorSignaling by Vascular endothelial growth factor
2VEGFA-KDRVEGFA_HUMAN - VGFR2_HUMANLigand-ReceptorSignaling by Vascular endothelial growth factor

II. Literature review

[source]
Namevascular endothelial growth factor receptor-2 signaling pathway
IDGO_0036324
collection_id

Biological process

Exact synonym

FLK-1 signaling pathway, KDR signaling pathway, VEGFR-2 signaling pathway, VEGFR2 signaling pathway

Description

The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor-2 (VEGFR-2) on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

External URL
Genes
SLC31A1CLEC14AKDRPDCD6VEGFADAB2IP