Genes | Cell types | No. of supported studies | |
|---|---|---|---|
| Group 1 | 5 studies | ||
| Group 2 | 105 studies | ||
| Group 3 | 26 studies |
| Name | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway |
| ID | GO_0035872 |
| collection_id | Biological process |
| Exact synonym | NLR signaling pathway, nucleotide-binding domain leucine-rich repeat containing receptor signaling pathway, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction, nucleotide-binding domain, leucine rich repeat containing receptor signal transduction pathway, nucleotide-binding domain, leucine rich repeat containing receptor signalling pathway |
| Description | The series of molecular signals initiated by a ligand binding to a nucleotide-binding domain, leucine rich repeat containing receptor (NLR), and ending with the regulation of a downstream cellular process. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. |
| Related synonym | NOD-like receptor signaling pathway |
| External URL | |
| Genes |