| Name | fatty acid elongase activity |
| ID | GO_0009922 |
| collection_id | Molecular function |
| Exact synonym | ELOVL, elongation of very long chain fatty acids activity, very-long-chain 3-ketoacyl-CoA synthase, very-long-chain 3-oxoacyl-CoA synthase, very-long-chain beta-ketoacyl-CoA synthase |
| Description | Catalysis of the reaction: a very-long-chain acyl-CoA + H+ + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA. This reaction is the first (condensation) step of the four-step fatty acid elongation cycle in the endoplasmic reticulum that extends fatty acids of C-16 or longer with an additional 2-C unit. |
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| Genes |