Molecular function

Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.

5' nucleotide phosphodiesterase/alkaline phosphodiesterase I activity, 5'-NPDase activity, 5'-PDE activity, 5'-PDase activity, 5'-exonuclease activity, 5'-nucleotide phosphodiesterase activity, 5'-phosphodiesterase activity, 5'NPDE activity, PDE I activity, alkaline phosphodiesterase activity, exonuclease I activity, nucleotide pyrophosphatase/phosphodiesterase I activity, oligonucleate 5'-nucleotidohydrolase activity, orthophosphoric diester phosphohydrolase activity