Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 19 studies | 31% ± 14% | |
astrocyte | 16 studies | 43% ± 19% | |
endothelial cell of lymphatic vessel | 14 studies | 44% ± 24% | |
oligodendrocyte precursor cell | 11 studies | 42% ± 15% | |
fibroblast | 9 studies | 32% ± 10% | |
mast cell | 8 studies | 27% ± 8% | |
oligodendrocyte | 8 studies | 29% ± 13% | |
vein endothelial cell | 7 studies | 31% ± 23% | |
adipocyte | 7 studies | 28% ± 8% | |
GABAergic neuron | 6 studies | 30% ± 8% | |
pericyte | 6 studies | 21% ± 5% | |
glutamatergic neuron | 5 studies | 54% ± 14% | |
cardiac muscle cell | 5 studies | 25% ± 5% | |
smooth muscle cell | 4 studies | 25% ± 10% | |
interneuron | 4 studies | 51% ± 21% | |
neuron | 4 studies | 44% ± 18% | |
epithelial cell | 3 studies | 43% ± 9% | |
granule cell | 3 studies | 73% ± 10% | |
OFF-bipolar cell | 3 studies | 30% ± 8% | |
ON-bipolar cell | 3 studies | 46% ± 24% | |
endothelial cell of vascular tree | 3 studies | 36% ± 16% | |
amacrine cell | 3 studies | 33% ± 17% | |
ependymal cell | 3 studies | 40% ± 19% | |
megakaryocyte-erythroid progenitor cell | 3 studies | 32% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 99% | 3108.86 | 2626 / 2642 | 98% | 26.67 | 690 / 705 |
breast | 100% | 2494.89 | 459 / 459 | 91% | 16.17 | 1015 / 1118 |
thymus | 100% | 1529.37 | 650 / 653 | 68% | 6.31 | 412 / 605 |
ovary | 100% | 2520.60 | 180 / 180 | 55% | 7.05 | 235 / 430 |
lung | 97% | 952.66 | 562 / 578 | 55% | 4.33 | 639 / 1155 |
skin | 98% | 1154.33 | 1775 / 1809 | 54% | 7.58 | 256 / 472 |
adrenal gland | 100% | 2221.69 | 258 / 258 | 51% | 7.79 | 118 / 230 |
esophagus | 92% | 793.16 | 1326 / 1445 | 56% | 4.22 | 103 / 183 |
kidney | 92% | 522.00 | 82 / 89 | 52% | 5.65 | 472 / 901 |
uterus | 100% | 2276.38 | 170 / 170 | 33% | 5.71 | 152 / 459 |
bladder | 100% | 1213.24 | 21 / 21 | 27% | 1.88 | 136 / 504 |
intestine | 93% | 896.55 | 899 / 966 | 31% | 2.25 | 162 / 527 |
prostate | 79% | 551.65 | 193 / 245 | 28% | 1.23 | 141 / 502 |
stomach | 58% | 386.11 | 210 / 359 | 48% | 3.58 | 136 / 286 |
adipose | 100% | 2467.13 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 2367.32 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 93% | 951.61 | 801 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 92% | 854.01 | 1223 / 1335 | 0% | 0 | 0 / 0 |
pancreas | 6% | 27.16 | 21 / 328 | 80% | 8.02 | 142 / 178 |
muscle | 71% | 346.03 | 574 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 31% | 2.25 | 14 / 45 |
eye | 0% | 0 | 0 / 0 | 21% | 1.56 | 17 / 80 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.40 | 3 / 29 |
liver | 1% | 5.77 | 3 / 226 | 5% | 0.32 | 21 / 406 |
peripheral blood | 0% | 0.71 | 2 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0048663 | Biological process | neuron fate commitment |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0019904 | Molecular function | protein domain specific binding |
GO_0005515 | Molecular function | protein binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ZNF521 |
Protein name | Zinc finger protein 521 (Early hematopoietic zinc finger protein) (LYST-interacting protein 3) ZNF521 protein Zinc finger protein 521 |
Synonyms | LIP3 EHZF |
Description | FUNCTION: Transcription factor that can both act as an activator or a repressor depending on the context. Involved in BMP signaling and in the regulation of the immature compartment of the hematopoietic system. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved specification of B-cell lineage; this interaction preventing EBF1 to bind DNA and activate target genes. . |
Accessions | ENST00000584787.5 ENST00000577801.5 ENST00000577775.1 H7BYU6 J3QRW6 Q96K83 ENST00000361524.8 ENST00000580488.1 ENST00000399425.6 J3QQI2 J3KT07 Q8IYZ2 J3KSZ4 J3KTI4 ENST00000577461.1 ENST00000538137.6 |