Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 17 studies | 33% ± 15% | |
endothelial cell | 16 studies | 30% ± 11% | |
macrophage | 12 studies | 22% ± 7% | |
fibroblast | 10 studies | 23% ± 8% | |
pericyte | 9 studies | 23% ± 4% | |
epithelial cell | 8 studies | 39% ± 20% | |
endothelial cell of lymphatic vessel | 7 studies | 20% ± 5% | |
smooth muscle cell | 7 studies | 22% ± 5% | |
basal cell | 7 studies | 32% ± 14% | |
mast cell | 6 studies | 26% ± 7% | |
astrocyte | 6 studies | 23% ± 7% | |
classical monocyte | 5 studies | 23% ± 6% | |
glutamatergic neuron | 5 studies | 32% ± 18% | |
goblet cell | 5 studies | 26% ± 14% | |
non-classical monocyte | 4 studies | 28% ± 8% | |
conventional dendritic cell | 4 studies | 26% ± 8% | |
connective tissue cell | 4 studies | 20% ± 4% | |
microglial cell | 4 studies | 20% ± 3% | |
club cell | 4 studies | 26% ± 4% | |
Mueller cell | 4 studies | 22% ± 3% | |
respiratory goblet cell | 4 studies | 23% ± 11% | |
natural killer cell | 3 studies | 19% ± 4% | |
pancreatic A cell | 3 studies | 37% ± 8% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 19% ± 1% | |
capillary endothelial cell | 3 studies | 16% ± 1% | |
neuron | 3 studies | 29% ± 10% | |
myofibroblast cell | 3 studies | 23% ± 4% | |
myeloid cell | 3 studies | 28% ± 8% | |
squamous epithelial cell | 3 studies | 46% ± 23% | |
retina horizontal cell | 3 studies | 23% ± 7% | |
lymphocyte | 3 studies | 23% ± 7% | |
secretory cell | 3 studies | 27% ± 10% | |
endothelial cell of vascular tree | 3 studies | 20% ± 5% | |
GABAergic neuron | 3 studies | 37% ± 12% | |
abnormal cell | 3 studies | 24% ± 6% | |
enteroendocrine cell | 3 studies | 23% ± 9% | |
intestinal crypt stem cell | 3 studies | 17% ± 2% | |
transit amplifying cell | 3 studies | 22% ± 7% | |
oligodendrocyte | 3 studies | 24% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 6356.49 | 2642 / 2642 | 100% | 150.86 | 705 / 705 |
esophagus | 100% | 6340.47 | 1445 / 1445 | 100% | 95.90 | 183 / 183 |
intestine | 100% | 5357.24 | 966 / 966 | 100% | 111.34 | 527 / 527 |
ovary | 100% | 8254.34 | 180 / 180 | 100% | 123.50 | 430 / 430 |
prostate | 100% | 7134.81 | 245 / 245 | 100% | 129.87 | 502 / 502 |
stomach | 100% | 4638.18 | 359 / 359 | 100% | 100.22 | 286 / 286 |
lung | 100% | 5622.00 | 578 / 578 | 100% | 140.85 | 1154 / 1155 |
kidney | 100% | 5763.27 | 89 / 89 | 100% | 84.68 | 900 / 901 |
breast | 100% | 6487.47 | 459 / 459 | 100% | 119.61 | 1116 / 1118 |
bladder | 100% | 5208.71 | 21 / 21 | 100% | 121.27 | 503 / 504 |
skin | 100% | 6585.26 | 1809 / 1809 | 100% | 83.55 | 471 / 472 |
pancreas | 100% | 4470.96 | 328 / 328 | 99% | 102.88 | 177 / 178 |
uterus | 100% | 6148.32 | 170 / 170 | 99% | 129.58 | 456 / 459 |
thymus | 100% | 5765.96 | 653 / 653 | 99% | 73.35 | 600 / 605 |
liver | 100% | 3152.00 | 226 / 226 | 97% | 60.35 | 393 / 406 |
adrenal gland | 100% | 7264.00 | 258 / 258 | 96% | 78.79 | 220 / 230 |
adipose | 100% | 6078.91 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5556.82 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 5065.21 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 108.43 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 52.24 | 1 / 1 |
muscle | 99% | 2239.60 | 794 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 3152.83 | 850 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 97% | 43.92 | 28 / 29 |
eye | 0% | 0 | 0 / 0 | 95% | 51.63 | 76 / 80 |
peripheral blood | 87% | 2555.41 | 810 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000422 | Biological process | autophagy of mitochondrion |
GO_0030242 | Biological process | autophagy of peroxisome |
GO_0009267 | Biological process | cellular response to starvation |
GO_0061723 | Biological process | glycophagy |
GO_0044804 | Biological process | nucleophagy |
GO_0000045 | Biological process | autophagosome assembly |
GO_0006497 | Biological process | protein lipidation |
GO_0034497 | Biological process | protein localization to phagophore assembly site |
GO_0034045 | Cellular component | phagophore assembly site membrane |
GO_0005764 | Cellular component | lysosome |
GO_0005829 | Cellular component | cytosol |
GO_0019898 | Cellular component | extrinsic component of membrane |
GO_0000407 | Cellular component | phagophore assembly site |
GO_0062078 | Molecular function | TSC1-TSC2 complex binding |
GO_0080025 | Molecular function | phosphatidylinositol-3,5-bisphosphate binding |
GO_0032266 | Molecular function | phosphatidylinositol-3-phosphate binding |
GO_0005515 | Molecular function | protein binding |
Gene name | WDR45B |
Protein name | WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein) WD repeat domain 45B |
Synonyms | WDR45L WIPI3 |
Description | FUNCTION: Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation . Binds phosphatidylinositol 3-phosphate (PtdIns3P), and other phosphoinositides including PtdIns(3,5)P2, forming on membranes of the endoplasmic reticulum upon activation of the upstream ULK1 and PI3 kinases and is recruited at phagophore assembly sites where it regulates the elongation of nascent phagophores downstream of WIPI2 . In the cellular response to starvation, may also function together with the TSC1-TSC2 complex and RB1CC1 in the inhibition of the mTORC1 signaling pathway . . |
Accessions | Q5MNZ6 I3L3A5 I3L4L8 ENST00000576517.1 I3L4S6 ENST00000572583.5 I3L1D0 ENST00000571817.5 ENST00000392325.9 ENST00000573616.5 |