I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 17% ± 2% | |
| dendritic cell | 3 studies | 21% ± 5% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| classical monocyte | 3 studies | 17% ± 2% | |
| dendritic cell | 3 studies | 21% ± 5% |
Insufficient scRNA-seq data for expression of USF1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2573.22 | 1445 / 1445 | 100% | 45.61 | 183 / 183 |
| liver | 100% | 2273.46 | 226 / 226 | 100% | 68.87 | 406 / 406 |
| lung | 100% | 4678.66 | 578 / 578 | 100% | 83.54 | 1155 / 1155 |
| ovary | 100% | 2769.61 | 180 / 180 | 100% | 65.82 | 430 / 430 |
| skin | 100% | 2309.24 | 1809 / 1809 | 100% | 80.65 | 472 / 472 |
| thymus | 100% | 3082.53 | 653 / 653 | 100% | 81.48 | 605 / 605 |
| uterus | 100% | 3170.38 | 170 / 170 | 100% | 101.91 | 459 / 459 |
| brain | 100% | 2725.43 | 2638 / 2642 | 100% | 108.42 | 705 / 705 |
| breast | 100% | 3094.98 | 459 / 459 | 100% | 97.22 | 1116 / 1118 |
| stomach | 100% | 2337.16 | 359 / 359 | 100% | 51.66 | 285 / 286 |
| intestine | 100% | 3482.97 | 966 / 966 | 100% | 57.72 | 525 / 527 |
| prostate | 100% | 3445.57 | 245 / 245 | 100% | 52.58 | 500 / 502 |
| adrenal gland | 100% | 3122.14 | 258 / 258 | 100% | 54.33 | 229 / 230 |
| kidney | 100% | 2714.02 | 89 / 89 | 100% | 54.32 | 897 / 901 |
| pancreas | 100% | 1619.49 | 328 / 328 | 99% | 83.24 | 177 / 178 |
| bladder | 100% | 3020.57 | 21 / 21 | 99% | 102.29 | 500 / 504 |
| adipose | 100% | 3135.27 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 177.16 | 29 / 29 |
| spleen | 100% | 8104.12 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 84.23 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 55.74 | 1 / 1 |
| blood vessel | 100% | 2544.70 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| heart | 100% | 1712.34 | 859 / 861 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1993.62 | 801 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 100% | 5494.00 | 925 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 96% | 46.45 | 77 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000430 | Biological process | regulation of transcription from RNA polymerase II promoter by glucose |
| GO_0032869 | Biological process | cellular response to insulin stimulus |
| GO_0045990 | Biological process | carbon catabolite regulation of transcription |
| GO_0000432 | Biological process | positive regulation of transcription from RNA polymerase II promoter by glucose |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0051918 | Biological process | negative regulation of fibrinolysis |
| GO_0009411 | Biological process | response to UV |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0055088 | Biological process | lipid homeostasis |
| GO_0019086 | Biological process | late viral transcription |
| GO_0042593 | Biological process | glucose homeostasis |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005794 | Cellular component | Golgi apparatus |
| GO_0000785 | Cellular component | chromatin |
| GO_0005667 | Cellular component | transcription regulator complex |
| GO_0005634 | Cellular component | nucleus |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0043425 | Molecular function | bHLH transcription factor binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0043565 | Molecular function | sequence-specific DNA binding |
| GO_0044877 | Molecular function | protein-containing complex binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0019901 | Molecular function | protein kinase binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0005515 | Molecular function | protein binding |
| GO_0042826 | Molecular function | histone deacetylase binding |
| Gene name | USF1 |
| Protein name | Upstream transcription factor 1 Upstream stimulatory factor 1 Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1) |
| Synonyms | hCG_20846 USF BHLHB11 |
| Description | FUNCTION: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters. |
| Accessions | ENST00000368021.7 [P22415-1] ENST00000368019.5 H0YD59 ENST00000473969.6 A0A0S2Z4U5 E9PJ52 ENST00000368020.5 [P22415-1] ENST00000528768.5 ENST00000531842.1 E9PME6 P22415 E9PQA2 ENST00000534633.5 B1AQP1 |
