Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| hematopoietic precursor cell | 3 studies | 29% ± 11% | |
| erythroblast | 3 studies | 43% ± 24% | |
| epithelial cell | 3 studies | 29% ± 7% | |
| glutamatergic neuron | 3 studies | 18% ± 2% | |
| intestinal crypt stem cell | 3 studies | 19% ± 1% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 45% ± 16% |
Insufficient scRNA-seq data for expression of UNG at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 1340.95 | 21 / 21 | 100% | 90.75 | 504 / 504 |
| ovary | 100% | 1505.36 | 180 / 180 | 100% | 91.93 | 430 / 430 |
| skin | 100% | 3051.96 | 1809 / 1809 | 100% | 62.60 | 472 / 472 |
| esophagus | 100% | 1680.19 | 1442 / 1445 | 100% | 60.11 | 183 / 183 |
| uterus | 100% | 1451.53 | 170 / 170 | 100% | 106.74 | 458 / 459 |
| brain | 100% | 1586.49 | 2636 / 2642 | 100% | 60.72 | 705 / 705 |
| breast | 100% | 2092.59 | 459 / 459 | 100% | 84.05 | 1114 / 1118 |
| adrenal gland | 100% | 5708.14 | 258 / 258 | 100% | 75.55 | 229 / 230 |
| thymus | 100% | 1817.96 | 653 / 653 | 100% | 59.50 | 602 / 605 |
| kidney | 100% | 1903.89 | 89 / 89 | 99% | 54.26 | 896 / 901 |
| intestine | 100% | 1693.72 | 965 / 966 | 99% | 86.40 | 524 / 527 |
| stomach | 100% | 1401.47 | 359 / 359 | 99% | 72.95 | 284 / 286 |
| prostate | 100% | 1337.47 | 245 / 245 | 99% | 50.05 | 498 / 502 |
| liver | 100% | 1353.09 | 226 / 226 | 98% | 47.10 | 399 / 406 |
| lung | 97% | 1024.75 | 562 / 578 | 100% | 73.66 | 1152 / 1155 |
| pancreas | 96% | 737.29 | 314 / 328 | 98% | 44.80 | 175 / 178 |
| adipose | 100% | 2073.61 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 66.47 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 65.40 | 29 / 29 |
| spleen | 100% | 1654.83 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 117.94 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 74.19 | 1 / 1 |
| muscle | 100% | 2449.11 | 802 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 97% | 794.40 | 1297 / 1335 | 0% | 0 | 0 / 0 |
| heart | 96% | 1057.71 | 823 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 45% | 909.88 | 419 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0045190 | Biological process | isotype switching |
| GO_0016446 | Biological process | somatic hypermutation of immunoglobulin genes |
| GO_0097510 | Biological process | base-excision repair, AP site formation via deaminated base removal |
| GO_0043066 | Biological process | negative regulation of apoptotic process |
| GO_0045008 | Biological process | depyrimidination |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005634 | Cellular component | nucleus |
| GO_0004844 | Molecular function | uracil DNA N-glycosylase activity |
| GO_0043024 | Molecular function | ribosomal small subunit binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0003684 | Molecular function | damaged DNA binding |
| Gene name | UNG |
| Protein name | Uracil-DNA glycosylase (UDG) (EC 3.2.2.27) Uracil-DNA glycosylase (EC 3.2.2.27) Uracil DNA glycosylase |
| Synonyms | UNG15 DKFZp781L1143 DGU U81 UNG1 |
| Description | FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. . |
| Accessions | ENST00000699567.1 ENST00000699560.1 ENST00000242576.7 [P13051-1] A0A8V8TQ70 P13051 ENST00000699564.1 E5KTA5 A0A8V8TNW7 A0A8V8TNE1 A0A8V8TPS1 A0A8V8TNJ5 ENST00000699561.1 ENST00000446767.2 ENST00000699566.1 A0A126LB28 ENST00000699563.1 F5GYA2 ENST00000336865.6 [P13051-2] A0A8V8TNW2 Q68DM5 ENST00000539287.6 ENST00000699562.1 ENST00000699565.1 A0A8V8TPS7 E5KTA6 B4DRT6 Q6FHS8 A0A8V8TQ66 ENST00000699559.1 |
