uracil DNA N-glycosylase activity

I. Literature review

[source]
Nameuracil DNA N-glycosylase activity
IDGO_0004844
collection_id

Molecular function

Exact synonym

uracil-DNA glycosylase activity

Description

Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.

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Genes