Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 24% ± 8% | |
| glutamatergic neuron | 8 studies | 38% ± 25% | |
| epithelial cell | 6 studies | 29% ± 7% | |
| astrocyte | 5 studies | 26% ± 7% | |
| oligodendrocyte | 5 studies | 20% ± 4% | |
| microglial cell | 4 studies | 21% ± 4% | |
| GABAergic neuron | 4 studies | 48% ± 15% | |
| oligodendrocyte precursor cell | 4 studies | 25% ± 8% | |
| endothelial cell of lymphatic vessel | 4 studies | 19% ± 1% | |
| macrophage | 4 studies | 22% ± 4% | |
| interneuron | 4 studies | 40% ± 23% | |
| classical monocyte | 3 studies | 24% ± 6% | |
| neuron | 3 studies | 27% ± 6% | |
| myeloid cell | 3 studies | 16% ± 1% | |
| adipocyte | 3 studies | 21% ± 2% | |
| type I pneumocyte | 3 studies | 20% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| bladder | 100% | 6277.19 | 21 / 21 | 100% | 29.28 | 504 / 504 |
| breast | 100% | 5234.20 | 459 / 459 | 100% | 41.11 | 1118 / 1118 |
| esophagus | 100% | 5360.99 | 1445 / 1445 | 100% | 28.34 | 183 / 183 |
| intestine | 100% | 6254.82 | 966 / 966 | 100% | 31.94 | 527 / 527 |
| lung | 100% | 5031.06 | 578 / 578 | 100% | 26.23 | 1155 / 1155 |
| ovary | 100% | 4807.08 | 180 / 180 | 100% | 29.48 | 430 / 430 |
| prostate | 100% | 4793.50 | 245 / 245 | 100% | 23.72 | 501 / 502 |
| uterus | 100% | 5664.82 | 170 / 170 | 100% | 28.21 | 458 / 459 |
| stomach | 100% | 4224.45 | 359 / 359 | 100% | 30.05 | 285 / 286 |
| pancreas | 100% | 2825.56 | 328 / 328 | 99% | 23.50 | 177 / 178 |
| thymus | 100% | 4664.13 | 653 / 653 | 99% | 27.66 | 601 / 605 |
| brain | 99% | 3929.58 | 2622 / 2642 | 100% | 23.72 | 705 / 705 |
| skin | 100% | 5242.05 | 1809 / 1809 | 98% | 29.28 | 464 / 472 |
| liver | 100% | 2520.63 | 226 / 226 | 97% | 15.05 | 394 / 406 |
| kidney | 100% | 3370.49 | 89 / 89 | 96% | 14.72 | 864 / 901 |
| adrenal gland | 100% | 4058.50 | 258 / 258 | 94% | 14.02 | 217 / 230 |
| adipose | 100% | 4625.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 6513.42 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 29.73 | 29 / 29 |
| spleen | 100% | 5752.55 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 27.83 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.26 | 1 / 1 |
| muscle | 99% | 2053.63 | 796 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 2975.35 | 848 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 12.29 | 71 / 80 |
| peripheral blood | 79% | 2507.11 | 734 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001525 | Biological process | angiogenesis |
| GO_0032897 | Biological process | negative regulation of viral transcription |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0005515 | Molecular function | protein binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| Gene name | UBP1 |
| Protein name | Upstream binding protein 1 Upstream-binding protein 1 (Transcription factor LBP-1) |
| Synonyms | LBP1 |
| Description | FUNCTION: Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. . |
| Accessions | Q9NZI7 ENST00000411650.5 ENST00000456378.1 ENST00000283629.8 [Q9NZI7-1] F8WEP8 ENST00000447368.6 [Q9NZI7-4] C9JWL3 ENST00000283628.9 [Q9NZI7-1] |