Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| natural killer cell | 11 studies | 19% ± 2% | |
| endothelial cell | 7 studies | 20% ± 5% | |
| CD16-positive, CD56-dim natural killer cell, human | 7 studies | 20% ± 5% | |
| CD8-positive, alpha-beta T cell | 6 studies | 19% ± 5% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 21% ± 5% | |
| regulatory T cell | 5 studies | 19% ± 2% | |
| epithelial cell | 4 studies | 32% ± 8% | |
| ciliated cell | 4 studies | 24% ± 5% | |
| plasmacytoid dendritic cell | 4 studies | 18% ± 2% | |
| gamma-delta T cell | 4 studies | 25% ± 10% | |
| classical monocyte | 3 studies | 18% ± 2% | |
| non-classical monocyte | 3 studies | 23% ± 5% | |
| neuron | 3 studies | 24% ± 3% | |
| GABAergic neuron | 3 studies | 39% ± 5% | |
| glutamatergic neuron | 3 studies | 51% ± 5% | |
| basal cell | 3 studies | 24% ± 4% | |
| double negative thymocyte | 3 studies | 23% ± 6% | |
| mucosal invariant T cell | 3 studies | 18% ± 3% | |
| astrocyte | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1681.15 | 1445 / 1445 | 100% | 40.67 | 183 / 183 |
| brain | 100% | 1721.58 | 2640 / 2642 | 100% | 57.62 | 705 / 705 |
| breast | 100% | 1711.69 | 459 / 459 | 100% | 43.69 | 1116 / 1118 |
| uterus | 100% | 1886.12 | 170 / 170 | 100% | 45.17 | 458 / 459 |
| lung | 100% | 1639.76 | 576 / 578 | 100% | 49.34 | 1155 / 1155 |
| prostate | 100% | 1408.90 | 245 / 245 | 100% | 33.34 | 500 / 502 |
| ovary | 99% | 1401.32 | 179 / 180 | 100% | 32.95 | 430 / 430 |
| thymus | 100% | 1397.74 | 652 / 653 | 99% | 41.65 | 600 / 605 |
| stomach | 100% | 1220.16 | 359 / 359 | 98% | 32.56 | 280 / 286 |
| kidney | 100% | 1176.43 | 89 / 89 | 98% | 31.68 | 881 / 901 |
| pancreas | 99% | 865.60 | 324 / 328 | 99% | 36.28 | 176 / 178 |
| bladder | 100% | 1586.86 | 21 / 21 | 98% | 33.86 | 492 / 504 |
| adrenal gland | 100% | 1495.36 | 258 / 258 | 97% | 32.59 | 224 / 230 |
| intestine | 100% | 1427.59 | 966 / 966 | 97% | 33.68 | 513 / 527 |
| liver | 100% | 681.27 | 226 / 226 | 97% | 20.62 | 392 / 406 |
| skin | 100% | 1742.09 | 1809 / 1809 | 95% | 46.96 | 450 / 472 |
| blood vessel | 100% | 1863.74 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 53.54 | 29 / 29 |
| spleen | 100% | 1995.54 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 52.78 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 7.40 | 1 / 1 |
| adipose | 100% | 1671.36 | 1203 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 99% | 846.25 | 795 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 883.91 | 842 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 93% | 1650.22 | 868 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 21.43 | 68 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006470 | Biological process | protein dephosphorylation |
| GO_0090364 | Biological process | regulation of proteasome assembly |
| GO_0032780 | Biological process | negative regulation of ATP-dependent activity |
| GO_0005730 | Cellular component | nucleolus |
| GO_0005634 | Cellular component | nucleus |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005515 | Molecular function | protein binding |
| GO_1904855 | Molecular function | proteasome regulatory particle binding |
| GO_0017018 | Molecular function | myosin phosphatase activity |
| GO_0046872 | Molecular function | metal ion binding |
| GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
| Gene name | UBLCP1 |
| Protein name | Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) |
| Synonyms | |
| Description | FUNCTION: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity . Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1 . Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly . Has also been reported to stimulate the proteolytic activity of the 26S proteasome . . |
| Accessions | ENST00000296786.8 Q8WVY7 |