Name | Number of supported studies | Average coverage | |
---|---|---|---|
natural killer cell | 11 studies | 19% ± 2% | |
endothelial cell | 7 studies | 20% ± 5% | |
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 20% ± 5% | |
CD8-positive, alpha-beta T cell | 6 studies | 19% ± 5% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 21% ± 5% | |
regulatory T cell | 5 studies | 19% ± 2% | |
epithelial cell | 4 studies | 32% ± 8% | |
ciliated cell | 4 studies | 24% ± 5% | |
plasmacytoid dendritic cell | 4 studies | 18% ± 2% | |
gamma-delta T cell | 4 studies | 25% ± 10% | |
classical monocyte | 3 studies | 18% ± 2% | |
non-classical monocyte | 3 studies | 23% ± 5% | |
neuron | 3 studies | 24% ± 3% | |
GABAergic neuron | 3 studies | 39% ± 5% | |
glutamatergic neuron | 3 studies | 51% ± 5% | |
basal cell | 3 studies | 24% ± 4% | |
double negative thymocyte | 3 studies | 23% ± 6% | |
mucosal invariant T cell | 3 studies | 18% ± 3% | |
astrocyte | 3 studies | 19% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1681.15 | 1445 / 1445 | 100% | 40.67 | 183 / 183 |
brain | 100% | 1721.58 | 2640 / 2642 | 100% | 57.62 | 705 / 705 |
breast | 100% | 1711.69 | 459 / 459 | 100% | 43.69 | 1116 / 1118 |
uterus | 100% | 1886.12 | 170 / 170 | 100% | 45.17 | 458 / 459 |
lung | 100% | 1639.76 | 576 / 578 | 100% | 49.34 | 1155 / 1155 |
prostate | 100% | 1408.90 | 245 / 245 | 100% | 33.34 | 500 / 502 |
ovary | 99% | 1401.32 | 179 / 180 | 100% | 32.95 | 430 / 430 |
thymus | 100% | 1397.74 | 652 / 653 | 99% | 41.65 | 600 / 605 |
stomach | 100% | 1220.16 | 359 / 359 | 98% | 32.56 | 280 / 286 |
kidney | 100% | 1176.43 | 89 / 89 | 98% | 31.68 | 881 / 901 |
pancreas | 99% | 865.60 | 324 / 328 | 99% | 36.28 | 176 / 178 |
bladder | 100% | 1586.86 | 21 / 21 | 98% | 33.86 | 492 / 504 |
adrenal gland | 100% | 1495.36 | 258 / 258 | 97% | 32.59 | 224 / 230 |
intestine | 100% | 1427.59 | 966 / 966 | 97% | 33.68 | 513 / 527 |
liver | 100% | 681.27 | 226 / 226 | 97% | 20.62 | 392 / 406 |
skin | 100% | 1742.09 | 1809 / 1809 | 95% | 46.96 | 450 / 472 |
blood vessel | 100% | 1863.74 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 53.54 | 29 / 29 |
spleen | 100% | 1995.54 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 52.78 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.40 | 1 / 1 |
adipose | 100% | 1671.36 | 1203 / 1204 | 0% | 0 | 0 / 0 |
muscle | 99% | 846.25 | 795 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 883.91 | 842 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 93% | 1650.22 | 868 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 85% | 21.43 | 68 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006470 | Biological process | protein dephosphorylation |
GO_0090364 | Biological process | regulation of proteasome assembly |
GO_0032780 | Biological process | negative regulation of ATP-dependent activity |
GO_0005730 | Cellular component | nucleolus |
GO_0005634 | Cellular component | nucleus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005515 | Molecular function | protein binding |
GO_1904855 | Molecular function | proteasome regulatory particle binding |
GO_0017018 | Molecular function | myosin phosphatase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0004722 | Molecular function | protein serine/threonine phosphatase activity |
Gene name | UBLCP1 |
Protein name | Ubiquitin-like domain-containing CTD phosphatase 1 (EC 3.1.3.16) (Nuclear proteasome inhibitor UBLCP1) |
Synonyms | |
Description | FUNCTION: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity . Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1 . Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly . Has also been reported to stimulate the proteolytic activity of the 26S proteasome . . |
Accessions | ENST00000296786.8 Q8WVY7 |