UBE2F report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0045116Biological processprotein neddylation
GO_0043687Biological processpost-translational protein modification
GO_0005829Cellular componentcytosol
GO_0005634Cellular componentnucleus
GO_0019788Molecular functionNEDD8 transferase activity
GO_0061654Molecular functionNEDD8 conjugating enzyme activity
GO_0061663Molecular functionNEDD8 ligase activity
GO_0005515Molecular functionprotein binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameUBE2F
Protein nameUbiquitin conjugating enzyme E2 F (putative) (Ubiquitin-conjugating enzyme E2F (Putative), isoform CRA_f)
Ubiquitin conjugating enzyme E2 F (putative)
NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F)
SynonymshCG_2039446
NCE2
DescriptionFUNCTION: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. .

AccessionsENST00000417231.5
F8WDQ9
C9JF62
ENST00000455999.5
ENST00000272930.9 [Q969M7-1]
ENST00000445676.5
ENST00000409953.5 [Q969M7-7]
ENST00000433241.5 [Q969M7-4]
ENST00000416292.5
ENST00000439338.5
ENST00000612130.4 [Q969M7-1]
ENST00000414443.5 [Q969M7-3]
ENST00000434655.5
ENST00000440223.5
F2Z363
Q969M7
ENST00000454786.5
C9JSK8
G5E9R6
ENST00000434137.2
ENST00000409633.5 [Q969M7-6]
ENST00000441728.6 [Q969M7-5]
ENST00000409332.5
F8WFB7
ENST00000433568.5
C9J9P8
ENST00000439780.5
F8WB39
C9JFD2
F8WD80
ENST00000448502.5
F8WCT3
C9IZ93