Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 2336.82 | 1445 / 1445 | 100% | 9.42 | 183 / 183 |
liver | 100% | 1458.17 | 226 / 226 | 100% | 8.12 | 406 / 406 |
lung | 100% | 1927.73 | 578 / 578 | 100% | 10.89 | 1155 / 1155 |
pancreas | 100% | 2539.82 | 328 / 328 | 100% | 11.02 | 178 / 178 |
prostate | 100% | 2026.35 | 245 / 245 | 100% | 11.99 | 502 / 502 |
stomach | 100% | 1575.06 | 359 / 359 | 100% | 9.23 | 286 / 286 |
thymus | 100% | 2446.50 | 653 / 653 | 100% | 13.99 | 605 / 605 |
brain | 100% | 2010.55 | 2640 / 2642 | 100% | 11.43 | 705 / 705 |
bladder | 100% | 1986.95 | 21 / 21 | 100% | 10.08 | 503 / 504 |
uterus | 100% | 1808.96 | 170 / 170 | 100% | 10.36 | 458 / 459 |
ovary | 100% | 1130.57 | 180 / 180 | 100% | 8.44 | 429 / 430 |
breast | 100% | 1618.21 | 459 / 459 | 100% | 12.92 | 1115 / 1118 |
kidney | 100% | 1695.79 | 89 / 89 | 100% | 7.62 | 898 / 901 |
intestine | 100% | 2066.36 | 966 / 966 | 100% | 10.42 | 525 / 527 |
adrenal gland | 100% | 2082.33 | 258 / 258 | 100% | 10.71 | 229 / 230 |
skin | 100% | 1677.58 | 1807 / 1809 | 99% | 9.56 | 469 / 472 |
adipose | 100% | 1852.07 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.87 | 29 / 29 |
muscle | 100% | 2505.79 | 803 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 2837.83 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 1865.31 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 9.73 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.34 | 1 / 1 |
blood vessel | 100% | 2462.69 | 1334 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 2381.04 | 843 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 5.68 | 77 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045116 | Biological process | protein neddylation |
GO_0043687 | Biological process | post-translational protein modification |
GO_0005829 | Cellular component | cytosol |
GO_0005634 | Cellular component | nucleus |
GO_0019788 | Molecular function | NEDD8 transferase activity |
GO_0061654 | Molecular function | NEDD8 conjugating enzyme activity |
GO_0061663 | Molecular function | NEDD8 ligase activity |
GO_0005515 | Molecular function | protein binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | UBE2F |
Protein name | Ubiquitin conjugating enzyme E2 F (putative) (Ubiquitin-conjugating enzyme E2F (Putative), isoform CRA_f) Ubiquitin conjugating enzyme E2 F (putative) NEDD8-conjugating enzyme UBE2F (EC 2.3.2.32) (NEDD8 carrier protein UBE2F) (NEDD8 protein ligase UBE2F) (NEDD8-conjugating enzyme 2) (RING-type E3 NEDD8 transferase UBE2F) (Ubiquitin-conjugating enzyme E2 F) |
Synonyms | hCG_2039446 NCE2 |
Description | FUNCTION: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. . |
Accessions | ENST00000417231.5 F8WDQ9 C9JF62 ENST00000455999.5 ENST00000272930.9 [Q969M7-1] ENST00000445676.5 ENST00000409953.5 [Q969M7-7] ENST00000433241.5 [Q969M7-4] ENST00000416292.5 ENST00000439338.5 ENST00000612130.4 [Q969M7-1] ENST00000414443.5 [Q969M7-3] ENST00000434655.5 ENST00000440223.5 F2Z363 Q969M7 ENST00000454786.5 C9JSK8 G5E9R6 ENST00000434137.2 ENST00000409633.5 [Q969M7-6] ENST00000441728.6 [Q969M7-5] ENST00000409332.5 F8WFB7 ENST00000433568.5 C9J9P8 ENST00000439780.5 F8WB39 C9JFD2 F8WD80 ENST00000448502.5 F8WCT3 C9IZ93 |