UBAP2L report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007339Biological processbinding of sperm to zona pellucida
GO_0062029Biological processpositive regulation of stress granule assembly
GO_0034063Biological processstress granule assembly
GO_0061484Biological processhematopoietic stem cell homeostasis
GO_0031519Cellular componentPcG protein complex
GO_0005694Cellular componentchromosome
GO_0010494Cellular componentcytoplasmic stress granule
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameUBAP2L
Protein nameUbiquitin associated protein 2 like
Ubiquitin-associated protein 2-like (Protein NICE-4) (RNA polymerase II degradation factor UBAP2L)
SynonymsKIAA0144
NICE4
DescriptionFUNCTION: Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage . Plays an important role in the activity of long-term repopulating hematopoietic stem cells (LT-HSCs) (By similarity). Required for efficient formation of stress granules . .

AccessionsQ5VU81
ENST00000412596.5
Q5VU78
ENST00000437652.6
ENST00000707139.1
H7C2T8
Q5VU77
Q5VU79
ENST00000343815.10 [Q14157-1]
Q14157
ENST00000368504.6
ENST00000361546.6 [Q14157-2]
F8W726
ENST00000613315.4 [Q14157-4]
ENST00000456325.5
ENST00000433615.5
ENST00000441890.5
ENST00000428931.6 [Q14157-2]
ENST00000271877.11
A0AA34QVE6
ENST00000428595.1
H0Y5H6
Q5VU80