UBAP1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0036258Biological processmultivesicular body assembly
GO_0043162Biological processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0043328Biological processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO_0090148Biological processmembrane fission
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0010008Cellular componentendosome membrane
GO_0005829Cellular componentcytosol
GO_0000813Cellular componentESCRT I complex
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding
GO_0043130Molecular functionubiquitin binding

IV. Literature review

[source]
Gene nameUBAP1
Protein nameUbiquitin associated protein 1
Ubiquitin-associated protein 1 (UBAP-1) (Nasopharyngeal carcinoma-associated gene 20 protein)
SynonymsNAG20
DescriptionFUNCTION: Component of the ESCRT-I complex, a regulator of vesicular trafficking process . Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) . Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 . .

AccessionsA0A6G6AA68
ENST00000359544.2 [Q9NZ09-1]
ENST00000625521.2 [Q9NZ09-4]
ENST00000297661.9 [Q9NZ09-1]
ENST00000379186.8 [Q9NZ09-2]
A0A0D9SG79
ENST00000626262.2
Q9NZ09