TRIP6 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_1901224Biological processpositive regulation of non-canonical NF-kappaB signal transduction
GO_0043009Biological processchordate embryonic development
GO_0030335Biological processpositive regulation of cell migration
GO_0048041Biological processfocal adhesion assembly
GO_0001725Cellular componentstress fiber
GO_0005856Cellular componentcytoskeleton
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005925Cellular componentfocal adhesion
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0019900Molecular functionkinase binding
GO_0046966Molecular functionnuclear thyroid hormone receptor binding
GO_0005149Molecular functioninterleukin-1 receptor binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding
GO_0003723Molecular functionRNA binding

IV. Literature review

[source]
Gene nameTRIP6
Protein nameThyroid receptor-interacting protein 6 (TR-interacting protein 6) (TRIP-6) (Opa-interacting protein 1) (OIP-1) (Zyxin-related protein 1) (ZRP-1)
Thyroid hormone receptor interactor 6
SynonymsOIP1
DescriptionFUNCTION: Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor. .

AccessionsENST00000429658.1
ENST00000619988.4 [Q15654-3]
ENST00000437505.5 [Q15654-3]
H7BZE2
ENST00000417475.5 [Q15654-2]
Q15654
ENST00000200457.9 [Q15654-1]