TNFRSF9 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TNFRSF9 at tissue level.

III. Associated gene sets

GO_0006915Biological processapoptotic process
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0033084Biological processregulation of immature T cell proliferation in thymus
GO_0042127Biological processregulation of cell population proliferation
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0038023Molecular functionsignaling receptor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTNFRSF9
Protein nameTumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
TNF receptor superfamily member 9
SynonymsCD137
ILA
DescriptionFUNCTION: Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). .

AccessionsENST00000674210.1
A0A6I8PRR4
K7EJQ2
ENST00000474475.1
ENST00000377507.8
ENST00000492571.1
Q07011
K7EJ11