Name | Number of supported studies | Average coverage | |
---|---|---|---|
regulatory T cell | 7 studies | 29% ± 8% | |
CD8-positive, alpha-beta T cell | 4 studies | 27% ± 10% |
Insufficient scRNA-seq data for expression of TNFRSF9 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 97% | 86.47 | 561 / 578 | 81% | 3.64 | 939 / 1155 |
stomach | 55% | 15.94 | 196 / 359 | 66% | 2.06 | 188 / 286 |
intestine | 48% | 31.81 | 462 / 966 | 61% | 1.64 | 319 / 527 |
kidney | 52% | 17.01 | 46 / 89 | 53% | 3.33 | 479 / 901 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.22 | 29 / 29 |
spleen | 100% | 255.20 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 100% | 359.69 | 926 / 929 | 0% | 0 | 0 / 0 |
esophagus | 29% | 7.78 | 414 / 1445 | 69% | 2.31 | 127 / 183 |
tonsil | 0% | 0 | 0 / 0 | 96% | 6.74 | 43 / 45 |
breast | 38% | 10.73 | 173 / 459 | 56% | 1.81 | 624 / 1118 |
skin | 27% | 6.03 | 486 / 1809 | 61% | 3.87 | 288 / 472 |
pancreas | 31% | 8.16 | 102 / 328 | 56% | 1.47 | 99 / 178 |
bladder | 38% | 6.52 | 8 / 21 | 48% | 1.58 | 241 / 504 |
thymus | 47% | 21.45 | 307 / 653 | 36% | 1.12 | 220 / 605 |
uterus | 15% | 3.87 | 25 / 170 | 58% | 1.87 | 264 / 459 |
liver | 46% | 12.16 | 103 / 226 | 23% | 1.21 | 94 / 406 |
adipose | 52% | 18.25 | 626 / 1204 | 0% | 0 | 0 / 0 |
ovary | 7% | 1.03 | 13 / 180 | 43% | 1.05 | 185 / 430 |
adrenal gland | 39% | 27.20 | 100 / 258 | 7% | 0.26 | 16 / 230 |
prostate | 32% | 7.71 | 78 / 245 | 10% | 0.19 | 49 / 502 |
blood vessel | 37% | 11.18 | 499 / 1335 | 0% | 0 | 0 / 0 |
heart | 26% | 7.41 | 225 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 14% | 0.66 | 11 / 80 |
brain | 7% | 3.40 | 187 / 2642 | 4% | 0.09 | 25 / 705 |
muscle | 2% | 0.30 | 17 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006915 | Biological process | apoptotic process |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0033084 | Biological process | regulation of immature T cell proliferation in thymus |
GO_0042127 | Biological process | regulation of cell population proliferation |
GO_0009897 | Cellular component | external side of plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | TNFRSF9 |
Protein name | Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137) TNF receptor superfamily member 9 |
Synonyms | CD137 ILA |
Description | FUNCTION: Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). . |
Accessions | ENST00000674210.1 A0A6I8PRR4 K7EJQ2 ENST00000474475.1 ENST00000377507.8 ENST00000492571.1 Q07011 K7EJ11 |