TLN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007043Biological processcell-cell junction assembly
GO_0007155Biological processcell adhesion
GO_0098609Biological processcell-cell adhesion
GO_0099140Biological processpresynaptic actin cytoskeleton organization
GO_0001726Cellular componentruffle
GO_0015629Cellular componentactin cytoskeleton
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005925Cellular componentfocal adhesion
GO_0003779Molecular functionactin binding
GO_0005200Molecular functionstructural constituent of cytoskeleton
GO_0051015Molecular functionactin filament binding
GO_0005515Molecular functionprotein binding
GO_0005198Molecular functionstructural molecule activity
GO_0005178Molecular functionintegrin binding

IV. Literature review

[source]
Gene nameTLN2
Protein nameTalin 2
Talin-2
SynonymsKIAA0320
DescriptionFUNCTION: As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). .

AccessionsENST00000636159.2
ENST00000494733.5
G1UI21
Q9Y4G6
H0YMT1
ENST00000561311.5
A0A1B0GVU7
ENST00000472902.1
H0YN01
ENST00000636159