THSD4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0048251Biological processelastic fiber assembly
GO_0030198Biological processextracellular matrix organization
GO_0160054Biological processmicrofibril assembly
GO_0001527Cellular componentmicrofibril
GO_0070062Cellular componentextracellular exosome
GO_0062023Cellular componentcollagen-containing extracellular matrix
GO_0005201Molecular functionextracellular matrix structural constituent
GO_0016787Molecular functionhydrolase activity

IV. Literature review

[source]
Gene nameTHSD4
Protein nameThrombospondin type-1 domain-containing protein 4 (A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6) (ADAMTS-like protein 6) (ADAMTSL-6)
Thrombospondin type 1 domain containing 4
SynonymsUNQ9334/PRO34005
DescriptionFUNCTION: Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN. .

AccessionsENST00000261862.8 [Q6ZMP0-1]
ENST00000620694.1
Q6ZMP0
ENST00000357769.4 [Q6ZMP0-4]
A0A087X1T0
ENST00000355327.7 [Q6ZMP0-1]