THEMIS2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006954Biological processinflammatory response
GO_0007155Biological processcell adhesion
GO_0050852Biological processT cell receptor signaling pathway
GO_0050864Biological processregulation of B cell activation
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameTHEMIS2
Protein nameThymocyte selection associated family member 2
Protein THEMIS2 (Induced by contact to basement membrane 1 protein) (Protein ICB-1) (Thymocyte-expressed molecule involved in selection protein 2)
SynonymsC1orf38
ICB1
DescriptionFUNCTION: May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production . Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity). .

AccessionsENST00000373927.7 [Q5TEJ8-4]
ENST00000456990.1
ENST00000373925.5 [Q5TEJ8-2]
ENST00000427466.1
ENST00000373921.8 [Q5TEJ8-1]
ENST00000328928.11 [Q5TEJ8-5]
X6RK39
Q5TEJ8
Q5TEK2
H7C124
ENST00000442118.5