Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| macrophage | 31 studies | 30% ± 12% | |
| classical monocyte | 24 studies | 39% ± 16% | |
| non-classical monocyte | 23 studies | 44% ± 14% | |
| conventional dendritic cell | 22 studies | 30% ± 14% | |
| monocyte | 20 studies | 30% ± 7% | |
| plasmacytoid dendritic cell | 19 studies | 38% ± 12% | |
| natural killer cell | 17 studies | 21% ± 5% | |
| dendritic cell | 14 studies | 32% ± 16% | |
| myeloid cell | 14 studies | 32% ± 15% | |
| CD16-positive, CD56-dim natural killer cell, human | 11 studies | 27% ± 7% | |
| B cell | 8 studies | 22% ± 7% | |
| alveolar macrophage | 8 studies | 28% ± 10% | |
| memory B cell | 8 studies | 19% ± 4% | |
| mononuclear phagocyte | 5 studies | 36% ± 13% | |
| plasma cell | 5 studies | 23% ± 7% | |
| CD16-negative, CD56-bright natural killer cell, human | 5 studies | 19% ± 3% | |
| neutrophil | 4 studies | 22% ± 5% | |
| microglial cell | 4 studies | 19% ± 3% | |
| plasmablast | 3 studies | 29% ± 6% | |
| tissue-resident macrophage | 3 studies | 32% ± 13% | |
| intermediate monocyte | 3 studies | 56% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 6579.79 | 578 / 578 | 96% | 28.04 | 1111 / 1155 |
| thymus | 97% | 1740.07 | 635 / 653 | 97% | 33.29 | 584 / 605 |
| breast | 89% | 1557.60 | 408 / 459 | 90% | 16.01 | 1007 / 1118 |
| intestine | 89% | 1959.04 | 864 / 966 | 82% | 13.04 | 430 / 527 |
| kidney | 61% | 1102.47 | 54 / 89 | 92% | 27.44 | 833 / 901 |
| stomach | 61% | 737.22 | 220 / 359 | 87% | 14.14 | 249 / 286 |
| bladder | 71% | 926.14 | 15 / 21 | 75% | 14.99 | 380 / 504 |
| esophagus | 61% | 679.90 | 878 / 1445 | 86% | 13.57 | 157 / 183 |
| uterus | 54% | 539.26 | 91 / 170 | 91% | 18.17 | 419 / 459 |
| adrenal gland | 91% | 1436.25 | 236 / 258 | 50% | 7.66 | 115 / 230 |
| brain | 41% | 540.65 | 1086 / 2642 | 89% | 19.97 | 629 / 705 |
| skin | 32% | 251.98 | 578 / 1809 | 96% | 30.20 | 451 / 472 |
| ovary | 27% | 278.54 | 49 / 180 | 97% | 41.23 | 419 / 430 |
| prostate | 71% | 899.26 | 174 / 245 | 45% | 4.33 | 228 / 502 |
| pancreas | 18% | 186.90 | 60 / 328 | 94% | 26.41 | 168 / 178 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 85.14 | 29 / 29 |
| peripheral blood | 100% | 23969.98 | 929 / 929 | 0% | 0 | 0 / 0 |
| spleen | 100% | 17007.60 | 241 / 241 | 0% | 0 | 0 / 0 |
| adipose | 97% | 2634.39 | 1167 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 21.02 | 43 / 45 |
| liver | 38% | 409.61 | 86 / 226 | 44% | 5.95 | 180 / 406 |
| blood vessel | 67% | 1253.85 | 895 / 1335 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 59% | 7.81 | 47 / 80 |
| heart | 42% | 435.46 | 359 / 861 | 0% | 0 | 0 / 0 |
| muscle | 8% | 71.43 | 64 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0007155 | Biological process | cell adhesion |
| GO_0050852 | Biological process | T cell receptor signaling pathway |
| GO_0050864 | Biological process | regulation of B cell activation |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | THEMIS2 |
| Protein name | Thymocyte selection associated family member 2 Protein THEMIS2 (Induced by contact to basement membrane 1 protein) (Protein ICB-1) (Thymocyte-expressed molecule involved in selection protein 2) |
| Synonyms | C1orf38 ICB1 |
| Description | FUNCTION: May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production . Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity). . |
| Accessions | ENST00000373927.7 [Q5TEJ8-4] ENST00000456990.1 ENST00000373925.5 [Q5TEJ8-2] ENST00000427466.1 ENST00000373921.8 [Q5TEJ8-1] ENST00000328928.11 [Q5TEJ8-5] X6RK39 Q5TEJ8 Q5TEK2 H7C124 ENST00000442118.5 |