Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 5 studies | 24% ± 6% | |
oligodendrocyte | 5 studies | 23% ± 3% | |
endothelial cell | 4 studies | 27% ± 9% | |
epithelial cell | 4 studies | 21% ± 3% | |
retina horizontal cell | 4 studies | 20% ± 6% | |
mast cell | 4 studies | 19% ± 2% | |
glutamatergic neuron | 4 studies | 43% ± 17% | |
oligodendrocyte precursor cell | 4 studies | 24% ± 6% | |
microglial cell | 3 studies | 19% ± 3% | |
cardiac muscle cell | 3 studies | 17% ± 1% | |
GABAergic neuron | 3 studies | 43% ± 8% | |
basal cell | 3 studies | 19% ± 4% | |
interneuron | 3 studies | 35% ± 20% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 471.71 | 1445 / 1445 | 100% | 7.04 | 183 / 183 |
stomach | 100% | 377.62 | 359 / 359 | 100% | 9.49 | 286 / 286 |
thymus | 100% | 591.43 | 653 / 653 | 100% | 9.35 | 605 / 605 |
intestine | 100% | 481.19 | 966 / 966 | 100% | 10.91 | 526 / 527 |
breast | 100% | 403.23 | 459 / 459 | 99% | 7.59 | 1112 / 1118 |
brain | 99% | 311.90 | 2625 / 2642 | 100% | 5.65 | 704 / 705 |
uterus | 100% | 409.46 | 170 / 170 | 99% | 7.34 | 455 / 459 |
bladder | 100% | 506.14 | 21 / 21 | 99% | 8.32 | 499 / 504 |
prostate | 100% | 446.51 | 245 / 245 | 99% | 5.50 | 496 / 502 |
pancreas | 99% | 282.58 | 326 / 328 | 99% | 5.99 | 176 / 178 |
adrenal gland | 100% | 1153.74 | 258 / 258 | 98% | 8.88 | 226 / 230 |
lung | 98% | 361.01 | 569 / 578 | 100% | 7.97 | 1152 / 1155 |
kidney | 100% | 453.42 | 89 / 89 | 97% | 6.13 | 874 / 901 |
skin | 100% | 621.92 | 1809 / 1809 | 96% | 8.62 | 455 / 472 |
liver | 100% | 554.28 | 226 / 226 | 96% | 5.55 | 390 / 406 |
ovary | 99% | 431.76 | 179 / 180 | 94% | 4.34 | 406 / 430 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.83 | 29 / 29 |
muscle | 100% | 667.83 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 639.91 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 8.66 | 45 / 45 |
blood vessel | 100% | 432.41 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 339.15 | 1200 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 426.34 | 840 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 6.95 | 72 / 80 |
peripheral blood | 79% | 431.81 | 736 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0000154 | Biological process | rRNA modification |
GO_0006391 | Biological process | transcription initiation at mitochondrial promoter |
GO_0031167 | Biological process | rRNA methylation |
GO_0005759 | Cellular component | mitochondrial matrix |
GO_0042645 | Cellular component | mitochondrial nucleoid |
GO_1904047 | Molecular function | S-adenosyl-L-methionine binding |
GO_0003677 | Molecular function | DNA binding |
GO_0034246 | Molecular function | mitochondrial transcription factor activity |
GO_0000179 | Molecular function | rRNA (adenine-N6,N6-)-dimethyltransferase activity |
GO_0005515 | Molecular function | protein binding |
GO_0003723 | Molecular function | RNA binding |
Gene name | TFB1M |
Protein name | rRNA adenine N(6)-methyltransferase (EC 2.1.1.-) Dimethyladenosine transferase 1, mitochondrial (EC 2.1.1.-) (Mitochondrial 12S rRNA dimethylase 1) (Mitochondrial transcription factor B1) (h-mtTFB) (h-mtTFB1) (hTFB1M) (mtTFB1) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1) |
Synonyms | hCG_32337 CGI-75 |
Description | FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. . FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. . |
Accessions | E5KTM5 ENST00000367166.5 Q8WVM0 |