Insufficient scRNA-seq data for expression of TBXT at single-cell level.
Insufficient scRNA-seq data for expression of TBXT at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 84% | 31.03 | 550 / 653 | 6% | 0.27 | 36 / 605 |
| spleen | 53% | 8.39 | 128 / 241 | 0% | 0 | 0 / 0 |
| adipose | 36% | 7.17 | 428 / 1204 | 0% | 0 | 0 / 0 |
| esophagus | 31% | 5.55 | 443 / 1445 | 2% | 0.04 | 4 / 183 |
| intestine | 25% | 2.24 | 238 / 966 | 3% | 0.08 | 14 / 527 |
| peripheral blood | 24% | 128.47 | 227 / 929 | 0% | 0 | 0 / 0 |
| breast | 21% | 3.02 | 95 / 459 | 1% | 0.04 | 10 / 1118 |
| lung | 11% | 0.89 | 65 / 578 | 10% | 0.63 | 117 / 1155 |
| stomach | 9% | 0.73 | 31 / 359 | 3% | 0.22 | 10 / 286 |
| skin | 10% | 0.65 | 185 / 1809 | 0% | 0 | 0 / 472 |
| brain | 9% | 0.67 | 241 / 2642 | 1% | 0.03 | 4 / 705 |
| prostate | 8% | 0.49 | 19 / 245 | 0% | 0 | 0 / 502 |
| bladder | 5% | 0.19 | 1 / 21 | 3% | 0.10 | 14 / 504 |
| ovary | 6% | 0.59 | 10 / 180 | 2% | 0.08 | 7 / 430 |
| uterus | 5% | 0.26 | 9 / 170 | 2% | 0.03 | 7 / 459 |
| kidney | 7% | 0.33 | 6 / 89 | 0% | 0 | 0 / 901 |
| blood vessel | 6% | 0.54 | 78 / 1335 | 0% | 0 | 0 / 0 |
| heart | 6% | 0.29 | 48 / 861 | 0% | 0 | 0 / 0 |
| adrenal gland | 3% | 0.29 | 9 / 258 | 0% | 0 | 0 / 230 |
| muscle | 3% | 0.19 | 28 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.44 | 1 / 29 |
| pancreas | 2% | 0.07 | 5 / 328 | 2% | 0.03 | 3 / 178 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.05 | 1 / 45 |
| liver | 2% | 0.11 | 4 / 226 | 0% | 0 | 0 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007498 | Biological process | mesoderm development |
| GO_0001708 | Biological process | cell fate specification |
| GO_0090009 | Biological process | primitive streak formation |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0007165 | Biological process | signal transduction |
| GO_0008595 | Biological process | anterior/posterior axis specification, embryo |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0043433 | Biological process | negative regulation of DNA-binding transcription factor activity |
| GO_0001707 | Biological process | mesoderm formation |
| GO_0060379 | Biological process | cardiac muscle cell myoblast differentiation |
| GO_0001756 | Biological process | somitogenesis |
| GO_0003007 | Biological process | heart morphogenesis |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| Gene name | TBXT |
| Protein name | T-box transcription factor T (Brachyury protein) (Protein T) Troponin T protein |
| Synonyms | T troponin |
| Description | FUNCTION: Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation. Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site. . |
| Accessions | ENST00000461348.2 ENST00000366871.7 [O15178-2] J3KP65 ENST00000366876.7 V9H0A7 ENST00000296946.6 [O15178-1] O15178 H0YM91 |