Name | Number of supported studies | Average coverage | |
---|---|---|---|
microglial cell | 9 studies | 28% ± 11% | |
platelet | 4 studies | 23% ± 7% | |
megakaryocyte-erythroid progenitor cell | 4 studies | 38% ± 18% | |
erythrocyte | 4 studies | 43% ± 19% | |
glomerular endothelial cell | 3 studies | 16% ± 1% | |
megakaryocyte | 3 studies | 37% ± 11% | |
endothelial cell | 3 studies | 19% ± 1% | |
erythroblast | 3 studies | 60% ± 20% |
Insufficient scRNA-seq data for expression of TAL1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 1344.44 | 653 / 653 | 74% | 2.22 | 445 / 605 |
brain | 75% | 329.80 | 1983 / 2642 | 98% | 6.69 | 693 / 705 |
kidney | 100% | 855.62 | 89 / 89 | 64% | 3.89 | 579 / 901 |
breast | 100% | 1484.32 | 459 / 459 | 64% | 1.49 | 710 / 1118 |
adrenal gland | 97% | 544.35 | 250 / 258 | 63% | 2.53 | 146 / 230 |
lung | 100% | 3052.16 | 578 / 578 | 47% | 1.14 | 543 / 1155 |
prostate | 96% | 520.47 | 236 / 245 | 44% | 0.69 | 219 / 502 |
esophagus | 95% | 586.74 | 1366 / 1445 | 32% | 0.78 | 58 / 183 |
bladder | 100% | 569.29 | 21 / 21 | 25% | 0.62 | 125 / 504 |
uterus | 99% | 876.12 | 169 / 170 | 23% | 0.60 | 105 / 459 |
intestine | 95% | 528.65 | 915 / 966 | 22% | 0.46 | 114 / 527 |
stomach | 83% | 326.12 | 297 / 359 | 30% | 0.53 | 85 / 286 |
adipose | 100% | 1571.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1630.48 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 98% | 602.24 | 848 / 861 | 0% | 0 | 0 / 0 |
pancreas | 22% | 51.82 | 72 / 328 | 65% | 1.61 | 116 / 178 |
peripheral blood | 81% | 978.55 | 751 / 929 | 0% | 0 | 0 / 0 |
skin | 59% | 251.47 | 1060 / 1809 | 15% | 0.32 | 70 / 472 |
liver | 46% | 142.27 | 103 / 226 | 25% | 0.47 | 102 / 406 |
blood vessel | 68% | 320.09 | 906 / 1335 | 0% | 0 | 0 / 0 |
ovary | 58% | 246.98 | 105 / 180 | 4% | 0.08 | 18 / 430 |
muscle | 58% | 152.01 | 469 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 13% | 0.18 | 6 / 45 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.14 | 3 / 29 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030221 | Biological process | basophil differentiation |
GO_0006366 | Biological process | transcription by RNA polymerase II |
GO_0001525 | Biological process | angiogenesis |
GO_0051781 | Biological process | positive regulation of cell division |
GO_0021527 | Biological process | spinal cord association neuron differentiation |
GO_0030097 | Biological process | hemopoiesis |
GO_0043249 | Biological process | erythrocyte maturation |
GO_0060375 | Biological process | regulation of mast cell differentiation |
GO_1904672 | Biological process | regulation of somatic stem cell population maintenance |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_1905269 | Biological process | positive regulation of chromatin organization |
GO_0035855 | Biological process | megakaryocyte development |
GO_0031334 | Biological process | positive regulation of protein-containing complex assembly |
GO_0060218 | Biological process | hematopoietic stem cell differentiation |
GO_0045931 | Biological process | positive regulation of mitotic cell cycle |
GO_0030218 | Biological process | erythrocyte differentiation |
GO_0060216 | Biological process | definitive hemopoiesis |
GO_0045165 | Biological process | cell fate commitment |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0045648 | Biological process | positive regulation of erythrocyte differentiation |
GO_0060018 | Biological process | astrocyte fate commitment |
GO_0030219 | Biological process | megakaryocyte differentiation |
GO_0030220 | Biological process | platelet formation |
GO_0035162 | Biological process | embryonic hemopoiesis |
GO_0007626 | Biological process | locomotory behavior |
GO_0042127 | Biological process | regulation of cell population proliferation |
GO_0060217 | Biological process | hemangioblast cell differentiation |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0005667 | Cellular component | transcription regulator complex |
GO_0005634 | Cellular component | nucleus |
GO_0019899 | Molecular function | enzyme binding |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003682 | Molecular function | chromatin binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_0061629 | Molecular function | RNA polymerase II-specific DNA-binding transcription factor binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0070888 | Molecular function | E-box binding |
GO_0046983 | Molecular function | protein dimerization activity |
GO_0005515 | Molecular function | protein binding |
GO_0042826 | Molecular function | histone deacetylase binding |
Gene name | TAL1 |
Protein name | Alternative protein TAL1 T-cell acute lymphocytic leukemia protein 1 (TAL-1) (Class A basic helix-loop-helix protein 17) (bHLHa17) (Stem cell protein) (T-cell leukemia/lymphoma protein 5) |
Synonyms | TCL5 SCL BHLHA17 |
Description | FUNCTION: Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of erythroid differentiation (By similarity). . |
Accessions | ENST00000294339.3 [P17542-1] ENST00000691006.1 [P17542-1] L8E8Z6 ENST00000371884.6 [P17542-1] P17542 |