Name | Number of supported studies | Average coverage | |
---|---|---|---|
regulatory T cell | 8 studies | 18% ± 3% | |
classical monocyte | 6 studies | 23% ± 8% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 5 studies | 17% ± 1% | |
platelet | 5 studies | 22% ± 5% | |
B cell | 4 studies | 21% ± 3% | |
CD4-positive, alpha-beta memory T cell | 4 studies | 17% ± 1% | |
hematopoietic precursor cell | 4 studies | 30% ± 14% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 17% ± 2% | |
CD4-positive, alpha-beta T cell | 4 studies | 22% ± 7% | |
conventional dendritic cell | 3 studies | 29% ± 10% | |
dendritic cell | 3 studies | 24% ± 2% | |
transit amplifying cell | 3 studies | 39% ± 10% | |
T cell | 3 studies | 18% ± 3% | |
hematopoietic stem cell | 3 studies | 29% ± 12% | |
CD8-positive, alpha-beta T cell | 3 studies | 23% ± 9% |
Insufficient scRNA-seq data for expression of TACC3 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 99% | 1188.67 | 574 / 578 | 97% | 25.63 | 1116 / 1155 |
intestine | 91% | 1038.21 | 879 / 966 | 98% | 29.82 | 517 / 527 |
bladder | 90% | 472.38 | 19 / 21 | 98% | 40.13 | 495 / 504 |
esophagus | 89% | 919.47 | 1279 / 1445 | 100% | 29.93 | 183 / 183 |
skin | 89% | 1735.93 | 1607 / 1809 | 99% | 28.41 | 468 / 472 |
breast | 81% | 439.28 | 374 / 459 | 95% | 21.84 | 1057 / 1118 |
stomach | 71% | 608.97 | 255 / 359 | 98% | 25.79 | 279 / 286 |
uterus | 66% | 310.74 | 112 / 170 | 100% | 50.49 | 458 / 459 |
ovary | 47% | 243.61 | 85 / 180 | 99% | 30.33 | 424 / 430 |
adrenal gland | 92% | 608.94 | 238 / 258 | 40% | 5.73 | 93 / 230 |
kidney | 65% | 436.20 | 58 / 89 | 46% | 5.24 | 418 / 901 |
thymus | 77% | 416.97 | 501 / 653 | 33% | 14.04 | 197 / 605 |
pancreas | 11% | 54.97 | 37 / 328 | 96% | 19.93 | 170 / 178 |
liver | 40% | 243.00 | 90 / 226 | 64% | 11.06 | 259 / 406 |
prostate | 71% | 385.71 | 174 / 245 | 31% | 3.49 | 156 / 502 |
lymph node | 0% | 0 | 0 / 0 | 100% | 89.08 | 29 / 29 |
peripheral blood | 100% | 8228.64 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 3650.38 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 47.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 30.53 | 1 / 1 |
adipose | 93% | 642.89 | 1119 / 1204 | 0% | 0 | 0 / 0 |
brain | 37% | 158.74 | 977 / 2642 | 54% | 14.53 | 383 / 705 |
heart | 59% | 286.00 | 511 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 59% | 5.55 | 47 / 80 |
blood vessel | 38% | 215.31 | 508 / 1335 | 0% | 0 | 0 / 0 |
muscle | 7% | 27.74 | 58 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007091 | Biological process | metaphase/anaphase transition of mitotic cell cycle |
GO_1902850 | Biological process | microtubule cytoskeleton organization involved in mitosis |
GO_0021987 | Biological process | cerebral cortex development |
GO_0060236 | Biological process | regulation of mitotic spindle organization |
GO_0051301 | Biological process | cell division |
GO_0008283 | Biological process | cell population proliferation |
GO_0007052 | Biological process | mitotic spindle organization |
GO_0000226 | Biological process | microtubule cytoskeleton organization |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0072686 | Cellular component | mitotic spindle |
GO_0005829 | Cellular component | cytosol |
GO_0034451 | Cellular component | centriolar satellite |
GO_0000922 | Cellular component | spindle pole |
GO_0005737 | Cellular component | cytoplasm |
GO_0005515 | Molecular function | protein binding |
Gene name | TACC3 |
Protein name | Transforming acidic coiled-coil-containing protein 3 (ERIC-1) Transforming acidic coiled-coil containing protein 3 Transforming acidic coiled-coil containing protein 3 (Transforming, acidic coiled-coil containing protein 3, isoform CRA_b) |
Synonyms | hCG_18955 ERIC1 |
Description | FUNCTION: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as a component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension . May be involved in the control of cell growth and differentiation. May contribute to cancer . . |
Accessions | ENST00000651817.1 ENST00000470136.2 F8WC55 ENST00000612220.5 ENST00000493975.5 ENST00000458173.4 ENST00000652770.1 A0A494C117 ENST00000651472.1 Q9Y6A5 A0A087WUE2 C9JA91 A0A494BZT8 ENST00000467746.6 E7EMT0 ENST00000313288.9 H0Y8F2 |