SYNJ1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0046488Biological processphosphatidylinositol metabolic process
GO_0016191Biological processsynaptic vesicle uncoating
GO_0007612Biological processlearning
GO_0048488Biological processsynaptic vesicle endocytosis
GO_0061024Biological processmembrane organization
GO_0046856Biological processphosphatidylinositol dephosphorylation
GO_1904980Biological processpositive regulation of endosome organization
GO_0043647Biological processinositol phosphate metabolic process
GO_0036092Biological processphosphatidylinositol-3-phosphate biosynthetic process
GO_0016082Biological processsynaptic vesicle priming
GO_0006836Biological processneurotransmitter transport
GO_0006661Biological processphosphatidylinositol biosynthetic process
GO_0048489Biological processsynaptic vesicle transport
GO_0098793Cellular componentpresynapse
GO_0030117Cellular componentmembrane coat
GO_0005874Cellular componentmicrotubule
GO_0012506Cellular componentvesicle membrane
GO_0048471Cellular componentperinuclear region of cytoplasm
GO_0097060Cellular componentsynaptic membrane
GO_0043195Cellular componentterminal bouton
GO_0005829Cellular componentcytosol
GO_0030132Cellular componentclathrin coat of coated pit
GO_0004438Molecular functionphosphatidylinositol-3-phosphate phosphatase activity
GO_0052658Molecular functioninositol-1,4,5-trisphosphate 5-phosphatase activity
GO_0004439Molecular functionphosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO_0034595Molecular functionphosphatidylinositol phosphate 5-phosphatase activity
GO_0034596Molecular functionphosphatidylinositol phosphate 4-phosphatase activity
GO_0052629Molecular functionphosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
GO_0003723Molecular functionRNA binding
GO_0043812Molecular functionphosphatidylinositol-4-phosphate phosphatase activity
GO_0017124Molecular functionSH3 domain binding
GO_0043813Molecular functionphosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSYNJ1
Protein namephosphoinositide 5-phosphatase (EC 3.1.3.36)
Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1)
Synaptojanin 1
SynonymsKIAA0910
DescriptionFUNCTION: Phosphatase that acts on various phosphoinositides, including phosphatidylinositol 4-phosphate, phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate . Has a role in clathrin-mediated endocytosis (By similarity). Hydrolyzes PIP2 bound to actin regulatory proteins resulting in the rearrangement of actin filaments downstream of tyrosine kinase and ASH/GRB2 (By similarity). .

AccessionsENST00000382499.7
ENST00000456084.1
H7BZ56
ENST00000674308.1 [O43426-1]
B9EGN3
ENST00000382491.7
ENST00000418301.3
H7BZC2
O43426
Q05CZ1
ENST00000438952.5
ENST00000357345.7 [O43426-4]
ENST00000674204.1 [O43426-2]
ENST00000630077.3
J3KPK1
J3KQV8
C9J1Z6
ENST00000674351.1 [O43426-2]
ENST00000433931.7
C9JW66
Q1ZYQ4
C9JFZ1
ENST00000429236.5
A0A0D9SGJ6