SPRY1 | OmnibusX

Name	Number of supported studies	Average coverage
fibroblast	35 studies	33% ± 14%	Explore
endothelial cell	33 studies	40% ± 16%	Explore
pericyte	27 studies	39% ± 22%	Explore
endothelial cell of vascular tree	14 studies	53% ± 17%	Explore
smooth muscle cell	12 studies	27% ± 11%	Explore
connective tissue cell	12 studies	32% ± 12%	Explore
vein endothelial cell	12 studies	33% ± 17%	Explore
endothelial cell of lymphatic vessel	11 studies	34% ± 11%	Explore
myofibroblast cell	11 studies	36% ± 9%	Explore
capillary endothelial cell	9 studies	38% ± 18%	Explore
natural killer cell	9 studies	23% ± 6%	Explore
basal cell	7 studies	26% ± 9%	Explore
endothelial cell of artery	7 studies	41% ± 10%	Explore
gamma-delta T cell	6 studies	32% ± 10%	Explore
mesothelial cell	6 studies	29% ± 9%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	22% ± 4%	Explore
adventitial cell	5 studies	26% ± 8%	Explore
innate lymphoid cell	5 studies	31% ± 11%	Explore
glomerular endothelial cell	4 studies	49% ± 6%	Explore
T cell	4 studies	26% ± 15%	Explore
CD8-positive, alpha-beta T cell	4 studies	24% ± 7%	Explore
astrocyte	4 studies	41% ± 19%	Explore
group 3 innate lymphoid cell	4 studies	42% ± 7%	Explore
retinal bipolar neuron	3 studies	22% ± 2%	Explore
Mueller cell	3 studies	44% ± 9%	Explore
adipocyte	3 studies	45% ± 22%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	100%	11407.88	652 / 653	96%	94.62	583 / 605
prostate	98%	6116.48	241 / 245	95%	40.89	478 / 502
lung	99%	6787.55	570 / 578	94%	34.63	1082 / 1155
breast	100%	18325.53	459 / 459	89%	36.40	999 / 1118
esophagus	90%	5989.55	1296 / 1445	93%	33.91	171 / 183
intestine	83%	4144.27	803 / 966	98%	33.21	515 / 527
bladder	95%	8137.10	20 / 21	86%	25.13	431 / 504
ovary	73%	3038.09	131 / 180	99%	76.86	424 / 430
adrenal gland	81%	3249.15	208 / 258	83%	36.99	192 / 230
stomach	65%	2991.50	234 / 359	98%	38.30	281 / 286
skin	77%	5946.42	1389 / 1809	83%	51.09	392 / 472
uterus	96%	7856.56	164 / 170	59%	25.03	273 / 459
kidney	69%	3494.52	61 / 89	79%	71.14	710 / 901
pancreas	34%	889.98	112 / 328	98%	49.70	175 / 178
adipose	100%	26193.59	1204 / 1204	0%	0	0 / 0
blood vessel	99%	8214.21	1322 / 1335	0%	0	0 / 0
heart	93%	5012.47	800 / 861	0%	0	0 / 0
muscle	84%	3288.67	673 / 803	0%	0	0 / 0
liver	24%	567.88	54 / 226	57%	11.90	230 / 406
eye	0%	0	0 / 0	78%	32.09	62 / 80
tonsil	0%	0	0 / 0	53%	9.08	24 / 45
brain	1%	14.58	19 / 2642	45%	18.88	319 / 705
spleen	37%	795.94	90 / 241	0%	0	0 / 0
lymph node	0%	0	0 / 0	14%	2.38	4 / 29
peripheral blood	0%	2.04	1 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0001657	Biological process	ureteric bud development
GO_0001759	Biological process	organ induction
GO_0030512	Biological process	negative regulation of transforming growth factor beta receptor signaling pathway
GO_0060449	Biological process	bud elongation involved in lung branching
GO_0001656	Biological process	metanephros development
GO_0070373	Biological process	negative regulation of ERK1 and ERK2 cascade
GO_0000132	Biological process	establishment of mitotic spindle orientation
GO_0046580	Biological process	negative regulation of Ras protein signal transduction
GO_0048513	Biological process	animal organ development
GO_1902747	Biological process	negative regulation of lens fiber cell differentiation
GO_0070371	Biological process	ERK1 and ERK2 cascade
GO_0010719	Biological process	negative regulation of epithelial to mesenchymal transition
GO_0043407	Biological process	negative regulation of MAP kinase activity
GO_0060940	Biological process	epithelial to mesenchymal transition involved in cardiac fibroblast development
GO_0051387	Biological process	negative regulation of neurotrophin TRK receptor signaling pathway
GO_0040037	Biological process	negative regulation of fibroblast growth factor receptor signaling pathway
GO_0005886	Cellular component	plasma membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005794	Cellular component	Golgi apparatus
GO_0005829	Cellular component	cytosol
GO_0005515	Molecular function	protein binding

Gene name	SPRY1
Protein name	Sprouty RTK signaling antagonist 1 Alternative protein SPRY1 Protein sprouty homolog 1 (Spry-1)
Synonyms
Description	FUNCTION: Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). .
Accessions	ENST00000508849.1 ENST00000505319.5 D6REX7 ENST00000651917.1 O43609 L8E896 D6RIE6 ENST00000339241.1 D6RHD2 ENST00000622283.1 ENST00000610581.4 ENST00000394339.2 ENST00000507703.1

SPRY1 report