Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 26 studies | 36% ± 19% | |
endothelial cell | 18 studies | 31% ± 13% | |
astrocyte | 17 studies | 44% ± 16% | |
oligodendrocyte precursor cell | 15 studies | 50% ± 21% | |
fibroblast | 13 studies | 28% ± 10% | |
pericyte | 13 studies | 30% ± 13% | |
microglial cell | 12 studies | 55% ± 18% | |
oligodendrocyte | 11 studies | 34% ± 11% | |
type I pneumocyte | 9 studies | 30% ± 13% | |
glutamatergic neuron | 9 studies | 40% ± 26% | |
myeloid cell | 9 studies | 42% ± 20% | |
GABAergic neuron | 8 studies | 39% ± 20% | |
epithelial cell | 7 studies | 25% ± 9% | |
interneuron | 6 studies | 34% ± 14% | |
monocyte | 6 studies | 33% ± 9% | |
mast cell | 6 studies | 27% ± 8% | |
dendritic cell | 5 studies | 23% ± 6% | |
smooth muscle cell | 5 studies | 30% ± 9% | |
abnormal cell | 4 studies | 22% ± 4% | |
neuron | 4 studies | 27% ± 15% | |
mononuclear phagocyte | 4 studies | 30% ± 10% | |
endothelial cell of lymphatic vessel | 4 studies | 25% ± 6% | |
alveolar macrophage | 4 studies | 38% ± 18% | |
type II pneumocyte | 4 studies | 25% ± 5% | |
glial cell | 3 studies | 29% ± 7% | |
granule cell | 3 studies | 19% ± 1% | |
Mueller cell | 3 studies | 31% ± 7% | |
ependymal cell | 3 studies | 33% ± 9% | |
club cell | 3 studies | 27% ± 9% | |
basal cell | 3 studies | 41% ± 28% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 3854.23 | 2640 / 2642 | 100% | 42.56 | 704 / 705 |
esophagus | 99% | 1727.71 | 1435 / 1445 | 99% | 24.17 | 182 / 183 |
lung | 100% | 4212.62 | 578 / 578 | 99% | 28.90 | 1138 / 1155 |
breast | 100% | 3139.28 | 459 / 459 | 96% | 23.80 | 1075 / 1118 |
intestine | 100% | 2103.43 | 966 / 966 | 96% | 23.15 | 506 / 527 |
thymus | 100% | 5654.76 | 653 / 653 | 96% | 46.67 | 580 / 605 |
stomach | 98% | 1485.23 | 351 / 359 | 96% | 20.86 | 275 / 286 |
skin | 99% | 2755.51 | 1791 / 1809 | 94% | 56.19 | 445 / 472 |
kidney | 100% | 1747.70 | 89 / 89 | 90% | 25.23 | 814 / 901 |
ovary | 100% | 2355.57 | 180 / 180 | 90% | 14.09 | 388 / 430 |
uterus | 100% | 2516.01 | 170 / 170 | 86% | 14.33 | 394 / 459 |
bladder | 100% | 2315.33 | 21 / 21 | 81% | 16.39 | 407 / 504 |
adrenal gland | 100% | 1707.97 | 257 / 258 | 80% | 12.89 | 185 / 230 |
prostate | 100% | 2144.12 | 244 / 245 | 71% | 8.39 | 355 / 502 |
pancreas | 69% | 651.54 | 226 / 328 | 96% | 23.84 | 170 / 178 |
adipose | 100% | 3817.02 | 1204 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 1572.16 | 241 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3123.60 | 1332 / 1335 | 0% | 0 | 0 / 0 |
heart | 97% | 1440.76 | 839 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 15.06 | 41 / 45 |
liver | 59% | 451.87 | 134 / 226 | 31% | 4.68 | 124 / 406 |
lymph node | 0% | 0 | 0 / 0 | 86% | 10.90 | 25 / 29 |
eye | 0% | 0 | 0 / 0 | 64% | 9.31 | 51 / 80 |
muscle | 50% | 397.05 | 398 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 6% | 49.23 | 55 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0090051 | Biological process | negative regulation of cell migration involved in sprouting angiogenesis |
GO_0006469 | Biological process | negative regulation of protein kinase activity |
GO_0060979 | Biological process | vasculogenesis involved in coronary vascular morphogenesis |
GO_0030512 | Biological process | negative regulation of transforming growth factor beta receptor signaling pathway |
GO_0070373 | Biological process | negative regulation of ERK1 and ERK2 cascade |
GO_0043517 | Biological process | positive regulation of DNA damage response, signal transduction by p53 class mediator |
GO_0016525 | Biological process | negative regulation of angiogenesis |
GO_0010801 | Biological process | negative regulation of peptidyl-threonine phosphorylation |
GO_1902747 | Biological process | negative regulation of lens fiber cell differentiation |
GO_0090311 | Biological process | regulation of protein deacetylation |
GO_0010719 | Biological process | negative regulation of epithelial to mesenchymal transition |
GO_0043409 | Biological process | negative regulation of MAPK cascade |
GO_0043408 | Biological process | regulation of MAPK cascade |
GO_0005886 | Cellular component | plasma membrane |
GO_0031410 | Cellular component | cytoplasmic vesicle |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005901 | Cellular component | caveola |
GO_0030291 | Molecular function | protein serine/threonine kinase inhibitor activity |
GO_0019901 | Molecular function | protein kinase binding |
GO_0019902 | Molecular function | phosphatase binding |
GO_0005173 | Molecular function | stem cell factor receptor binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SPRED1 |
Protein name | Alternative protein SPRED1 Sprouty-related, EVH1 domain-containing protein 1 (Spred-1) (hSpred1) Sprouty related EVH1 domain containing 1 |
Synonyms | |
Description | FUNCTION: Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity). Negatively regulates hematopoiesis of bone marrow (By similarity). Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2 (By similarity). Attenuates actin stress fiber formation via inhibition of TESK1-mediated phosphorylation of cofilin . Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells (By similarity). . |
Accessions | H0YMN8 ENST00000561317.1 L8EBE5 Q7Z699 ENST00000299084.9 |