SP2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of SP2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SP2 at tissue level.

III. Associated gene sets

GO_0006955Biological processimmune response
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0042826Molecular functionhistone deacetylase binding
GO_0005515Molecular functionprotein binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameSP2
Protein nameTranscription factor Sp2
Sp2 transcription factor
SP2 protein
SynonymsKIAA0048
DescriptionFUNCTION: Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.

AccessionsA0A1B0GTK3
ENST00000376741.5 [Q02086-1]
A0A1B0GV29
A0A286YFJ7
ENST00000637314.1
ENST00000642065.1
Q02086
ENST00000637943.1
ENST00000635868.1
A0A1B0GVH1
Q9BRW5