SOX30 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of SOX30 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	99%	33.76	959 / 966	48%	1.47	254 / 527
uterus	86%	14.04	146 / 170	51%	2.57	232 / 459
esophagus	95%	18.49	1375 / 1445	40%	1.64	74 / 183
stomach	79%	10.92	285 / 359	37%	1.06	106 / 286
bladder	95%	21.71	20 / 21	18%	0.49	91 / 504
ovary	84%	9.95	152 / 180	27%	0.61	114 / 430
prostate	98%	30.83	240 / 245	6%	0.11	32 / 502
spleen	99%	17.21	238 / 241	0%	0	0 / 0
adrenal gland	91%	11.21	234 / 258	7%	0.14	15 / 230
thymus	90%	14.28	590 / 653	7%	0.11	40 / 605
lung	78%	9.55	449 / 578	19%	0.65	216 / 1155
kidney	92%	11.97	82 / 89	4%	0.08	34 / 901
breast	84%	14.70	385 / 459	5%	0.13	59 / 1118
blood vessel	88%	12.45	1176 / 1335	0%	0	0 / 0
adipose	83%	9.05	1004 / 1204	0%	0	0 / 0
heart	82%	14.09	707 / 861	0%	0	0 / 0
brain	70%	7.10	1853 / 2642	1%	0.02	10 / 705
pancreas	55%	3.56	180 / 328	16%	0.38	29 / 178
tonsil	0%	0	0 / 0	71%	5.49	32 / 45
skin	66%	7.05	1194 / 1809	5%	0.10	24 / 472
peripheral blood	51%	3.81	471 / 929	0%	0	0 / 0
liver	42%	3.38	96 / 226	0%	0.00	1 / 406
lymph node	0%	0	0 / 0	38%	1.29	11 / 29
muscle	28%	3.06	223 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006357	Biological process	regulation of transcription by RNA polymerase II
GO_0031960	Biological process	response to corticosteroid
GO_0000122	Biological process	negative regulation of transcription by RNA polymerase II
GO_0030178	Biological process	negative regulation of Wnt signaling pathway
GO_0120211	Biological process	proacrosomal vesicle fusion
GO_0007286	Biological process	spermatid development
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0010369	Cellular component	chromocenter
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0000785	Cellular component	chromatin
GO_0005634	Cellular component	nucleus
GO_0000978	Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228	Molecular function	DNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227	Molecular function	DNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981	Molecular function	DNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837	Molecular function	sequence-specific double-stranded DNA binding
GO_0008013	Molecular function	beta-catenin binding
GO_0005515	Molecular function	protein binding

Gene name	SOX30
Protein name	SRY-box transcription factor 30 (cDNA FLJ53881, highly similar to Transcription factor SOX-30) Transcription factor SOX-30
Synonyms
Description	FUNCTION: Acts both as a transcriptional activator and a repressor . Binds to the DNA sequence 5'-ACAAT-3' and shows a preference for guanine residues surrounding this core motif . Binds to its own promoter and activates its own transcription (By similarity). Required to activate the expression of postmeiotic genes involved in spermiogenesis (By similarity). Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling . Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 . .
Accessions	B4DXW7 ENST00000311371.9 [O94993-2] ENST00000519442.1 O94993 ENST00000265007.11 [O94993-1]

SOX30 report