SOX21 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SOX21 at tissue level.

III. Associated gene sets

GO_0007420Biological processbrain development
GO_0030182Biological processneuron differentiation
GO_0048863Biological processstem cell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006355Biological processregulation of DNA-templated transcription
GO_0001942Biological processhair follicle development
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0005575Cellular componentcellular_component
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific

IV. Literature review

[source]
Gene nameSOX21
Protein nameTranscription factor SOX-21 (SOX-A)
SynonymsSOX25
SOXA
DescriptionFUNCTION: May play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can up-regulate the OPRM1 distal promoter activity in mor-expressing neuronal cells. May play a role in ameloblast differentiation. .

AccessionsQ9Y651
ENST00000376945.4