Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 17 studies | 31% ± 14% | |
| oligodendrocyte | 15 studies | 50% ± 17% | |
| astrocyte | 13 studies | 32% ± 17% | |
| microglial cell | 11 studies | 33% ± 13% | |
| macrophage | 11 studies | 35% ± 16% | |
| fibroblast | 10 studies | 30% ± 11% | |
| adipocyte | 9 studies | 26% ± 9% | |
| oligodendrocyte precursor cell | 8 studies | 28% ± 11% | |
| myeloid cell | 7 studies | 27% ± 9% | |
| epithelial cell | 7 studies | 33% ± 14% | |
| dendritic cell | 7 studies | 24% ± 3% | |
| retinal rod cell | 6 studies | 25% ± 9% | |
| mast cell | 6 studies | 20% ± 4% | |
| endothelial cell of lymphatic vessel | 6 studies | 34% ± 11% | |
| retinal cone cell | 5 studies | 27% ± 7% | |
| ciliated cell | 5 studies | 31% ± 8% | |
| hepatocyte | 5 studies | 62% ± 26% | |
| GABAergic neuron | 5 studies | 41% ± 18% | |
| monocyte | 5 studies | 30% ± 10% | |
| type II pneumocyte | 5 studies | 25% ± 7% | |
| retinal pigment epithelial cell | 4 studies | 45% ± 16% | |
| Mueller cell | 4 studies | 27% ± 8% | |
| glutamatergic neuron | 4 studies | 44% ± 18% | |
| pericyte | 4 studies | 28% ± 6% | |
| smooth muscle cell | 4 studies | 20% ± 1% | |
| interneuron | 4 studies | 39% ± 24% | |
| cardiac muscle cell | 3 studies | 18% ± 2% | |
| non-classical monocyte | 3 studies | 19% ± 1% | |
| endothelial cell of vascular tree | 3 studies | 31% ± 13% | |
| abnormal cell | 3 studies | 34% ± 24% | |
| ependymal cell | 3 studies | 34% ± 17% | |
| alveolar macrophage | 3 studies | 47% ± 13% | |
| club cell | 3 studies | 20% ± 5% | |
| basal cell | 3 studies | 33% ± 16% | |
| transit amplifying cell | 3 studies | 35% ± 23% | |
| brush cell | 3 studies | 30% ± 8% | |
| neuron | 3 studies | 52% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| lung | 100% | 1455.99 | 578 / 578 | 100% | 35.33 | 1155 / 1155 |
| stomach | 100% | 1284.94 | 359 / 359 | 100% | 37.17 | 286 / 286 |
| ovary | 100% | 1294.60 | 180 / 180 | 100% | 32.57 | 429 / 430 |
| liver | 100% | 5791.72 | 226 / 226 | 100% | 82.88 | 405 / 406 |
| skin | 100% | 1658.31 | 1808 / 1809 | 100% | 87.42 | 471 / 472 |
| esophagus | 100% | 1149.53 | 1445 / 1445 | 99% | 40.80 | 182 / 183 |
| intestine | 100% | 1750.69 | 966 / 966 | 99% | 37.83 | 523 / 527 |
| bladder | 100% | 1218.19 | 21 / 21 | 99% | 33.49 | 500 / 504 |
| breast | 100% | 1524.55 | 459 / 459 | 99% | 29.01 | 1109 / 1118 |
| prostate | 100% | 1459.43 | 245 / 245 | 99% | 30.15 | 497 / 502 |
| kidney | 100% | 2019.42 | 89 / 89 | 99% | 36.19 | 891 / 901 |
| pancreas | 100% | 806.09 | 328 / 328 | 99% | 28.49 | 176 / 178 |
| uterus | 100% | 1182.01 | 170 / 170 | 99% | 31.27 | 453 / 459 |
| thymus | 100% | 1465.32 | 653 / 653 | 97% | 23.71 | 588 / 605 |
| brain | 98% | 791.12 | 2580 / 2642 | 99% | 27.09 | 701 / 705 |
| adrenal gland | 100% | 2187.84 | 258 / 258 | 92% | 25.40 | 212 / 230 |
| adipose | 100% | 1556.40 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 1673.75 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 28.44 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.46 | 1 / 1 |
| blood vessel | 100% | 1017.75 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 750.94 | 799 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 99% | 35.84 | 79 / 80 |
| heart | 98% | 700.18 | 846 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 20.42 | 28 / 29 |
| peripheral blood | 73% | 594.83 | 675 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070778 | Biological process | L-aspartate transmembrane transport |
| GO_0006754 | Biological process | ATP biosynthetic process |
| GO_0015813 | Biological process | L-glutamate transmembrane transport |
| GO_0015810 | Biological process | aspartate transmembrane transport |
| GO_0006839 | Biological process | mitochondrial transport |
| GO_0009066 | Biological process | aspartate family amino acid metabolic process |
| GO_0045333 | Biological process | cellular respiration |
| GO_0015804 | Biological process | neutral amino acid transport |
| GO_0006094 | Biological process | gluconeogenesis |
| GO_0043490 | Biological process | malate-aspartate shuttle |
| GO_0051592 | Biological process | response to calcium ion |
| GO_1902600 | Biological process | proton transmembrane transport |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0005743 | Cellular component | mitochondrial inner membrane |
| GO_0015172 | Molecular function | acidic amino acid transmembrane transporter activity |
| GO_0015183 | Molecular function | L-aspartate transmembrane transporter activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0000514 | Molecular function | 3-sulfino-L-alanine: proton, glutamate antiporter activity |
| GO_0005313 | Molecular function | L-glutamate transmembrane transporter activity |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0000515 | Molecular function | aspartate:glutamate, proton antiporter activity |
| Gene name | SLC25A13 |
| Protein name | Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial (Calcium-binding mitochondrial carrier protein Aralar2) (ARALAR-related gene 2) (ARALAR2) (Citrin) (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) Calcium uptake protein 1, mitochondrial Solute carrier family 25 member 13 Uncharacterized protein SLC25A13 |
| Synonyms | |
| Description | FUNCTION: Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle . Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation . . |
| Accessions | Q75KX8 Q9UJS0 ENST00000472162.2 R4GN64 Q75M55 ENST00000265631.10 [Q9UJS0-1] ENST00000416240.6 [Q9UJS0-2] |