Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 10 studies | 52% ± 25% | |
GABAergic neuron | 9 studies | 52% ± 25% | |
astrocyte | 9 studies | 36% ± 17% | |
endothelial cell | 9 studies | 31% ± 16% | |
fibroblast | 9 studies | 23% ± 7% | |
oligodendrocyte precursor cell | 8 studies | 37% ± 17% | |
adipocyte | 8 studies | 22% ± 5% | |
smooth muscle cell | 6 studies | 22% ± 5% | |
neuron | 5 studies | 35% ± 12% | |
interneuron | 5 studies | 66% ± 26% | |
retinal ganglion cell | 5 studies | 39% ± 13% | |
cardiac muscle cell | 5 studies | 51% ± 12% | |
oligodendrocyte | 5 studies | 30% ± 14% | |
granule cell | 4 studies | 33% ± 10% | |
amacrine cell | 4 studies | 26% ± 6% | |
retina horizontal cell | 4 studies | 24% ± 5% | |
retinal cone cell | 4 studies | 33% ± 7% | |
retinal rod cell | 4 studies | 22% ± 4% | |
macrophage | 3 studies | 26% ± 4% | |
microglial cell | 3 studies | 26% ± 6% | |
epithelial cell | 3 studies | 30% ± 11% | |
GABAergic amacrine cell | 3 studies | 26% ± 7% | |
ON-bipolar cell | 3 studies | 25% ± 3% | |
glycinergic amacrine cell | 3 studies | 25% ± 3% | |
pericyte | 3 studies | 34% ± 9% | |
type II pneumocyte | 3 studies | 16% ± 1% | |
lymphocyte | 3 studies | 21% ± 3% | |
basal cell | 3 studies | 29% ± 11% | |
endothelial cell of lymphatic vessel | 3 studies | 16% ± 0% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1991.61 | 459 / 459 | 100% | 17.63 | 1118 / 1118 |
ovary | 100% | 2401.90 | 180 / 180 | 100% | 13.18 | 430 / 430 |
uterus | 100% | 2131.98 | 170 / 170 | 100% | 14.59 | 459 / 459 |
thymus | 100% | 2916.00 | 653 / 653 | 100% | 18.57 | 604 / 605 |
prostate | 100% | 2483.78 | 245 / 245 | 100% | 14.05 | 501 / 502 |
kidney | 99% | 1883.64 | 88 / 89 | 100% | 15.53 | 899 / 901 |
intestine | 100% | 3137.01 | 966 / 966 | 98% | 11.31 | 518 / 527 |
esophagus | 100% | 3272.63 | 1444 / 1445 | 98% | 15.51 | 180 / 183 |
skin | 100% | 2052.40 | 1806 / 1809 | 97% | 14.09 | 460 / 472 |
bladder | 100% | 2656.19 | 21 / 21 | 97% | 11.84 | 490 / 504 |
adrenal gland | 98% | 1841.97 | 254 / 258 | 99% | 20.91 | 227 / 230 |
brain | 97% | 3074.51 | 2555 / 2642 | 100% | 22.94 | 705 / 705 |
stomach | 99% | 2052.63 | 357 / 359 | 95% | 10.58 | 272 / 286 |
lung | 95% | 1234.04 | 548 / 578 | 99% | 13.52 | 1149 / 1155 |
pancreas | 11% | 80.97 | 37 / 328 | 98% | 12.26 | 175 / 178 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.73 | 29 / 29 |
muscle | 100% | 9072.41 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 1614.39 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 15.48 | 45 / 45 |
blood vessel | 100% | 3033.60 | 1334 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 1716.88 | 1197 / 1204 | 0% | 0 | 0 / 0 |
heart | 96% | 5866.18 | 828 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 93% | 9.96 | 74 / 80 |
peripheral blood | 47% | 876.33 | 436 / 929 | 0% | 0 | 0 / 0 |
liver | 2% | 14.78 | 5 / 226 | 29% | 1.91 | 119 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0070778 | Biological process | L-aspartate transmembrane transport |
GO_0015813 | Biological process | L-glutamate transmembrane transport |
GO_0015810 | Biological process | aspartate transmembrane transport |
GO_0009066 | Biological process | aspartate family amino acid metabolic process |
GO_0015804 | Biological process | neutral amino acid transport |
GO_0006094 | Biological process | gluconeogenesis |
GO_0043490 | Biological process | malate-aspartate shuttle |
GO_0051592 | Biological process | response to calcium ion |
GO_1902600 | Biological process | proton transmembrane transport |
GO_0016020 | Cellular component | membrane |
GO_0005739 | Cellular component | mitochondrion |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0015172 | Molecular function | acidic amino acid transmembrane transporter activity |
GO_0015183 | Molecular function | L-aspartate transmembrane transporter activity |
GO_0042802 | Molecular function | identical protein binding |
GO_0000514 | Molecular function | 3-sulfino-L-alanine: proton, glutamate antiporter activity |
GO_0005313 | Molecular function | L-glutamate transmembrane transporter activity |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0000515 | Molecular function | aspartate:glutamate, proton antiporter activity |
Gene name | SLC25A12 |
Protein name | Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial (Araceli hiperlarga) (Aralar) (Aralar1) (Mitochondrial aspartate glutamate carrier 1) (Solute carrier family 25 member 12) Solute carrier family 25 member 12 Solute carrier family 25 member 12 (cDNA FLJ57722, highly similar to Calcium-binding mitochondrial carrier protein Aralar1) |
Synonyms | AGC1 ARALAR1 |
Description | FUNCTION: Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle . Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation . . |
Accessions | O75746 ENST00000426896.5 B4DGK6 ENST00000263812.8 ENST00000709717.1 [O75746-1] F8W9J0 H0YFB2 ENST00000422440.7 [O75746-1] ENST00000475360.6 |