Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 25% ± 10% | |
retinal cone cell | 7 studies | 28% ± 8% | |
oligodendrocyte | 7 studies | 25% ± 7% | |
microglial cell | 6 studies | 27% ± 8% | |
GABAergic neuron | 6 studies | 37% ± 19% | |
macrophage | 6 studies | 27% ± 3% | |
glutamatergic neuron | 5 studies | 45% ± 21% | |
B cell | 5 studies | 23% ± 8% | |
astrocyte | 5 studies | 30% ± 10% | |
oligodendrocyte precursor cell | 5 studies | 29% ± 8% | |
monocyte | 5 studies | 33% ± 9% | |
squamous epithelial cell | 4 studies | 42% ± 16% | |
classical monocyte | 4 studies | 23% ± 7% | |
myeloid cell | 4 studies | 30% ± 17% | |
dendritic cell | 4 studies | 25% ± 6% | |
retinal rod cell | 4 studies | 29% ± 9% | |
endothelial cell of lymphatic vessel | 4 studies | 24% ± 3% | |
interneuron | 4 studies | 40% ± 21% | |
neutrophil | 3 studies | 21% ± 3% | |
plasma cell | 3 studies | 27% ± 5% | |
epithelial cell | 3 studies | 43% ± 14% | |
alveolar macrophage | 3 studies | 37% ± 11% | |
cardiac muscle cell | 3 studies | 17% ± 1% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 3118.84 | 1440 / 1445 | 100% | 22.24 | 183 / 183 |
lung | 100% | 3452.30 | 577 / 578 | 98% | 14.36 | 1137 / 1155 |
brain | 99% | 2102.05 | 2612 / 2642 | 99% | 16.83 | 696 / 705 |
thymus | 100% | 2941.18 | 653 / 653 | 96% | 11.08 | 581 / 605 |
kidney | 100% | 1864.84 | 89 / 89 | 95% | 11.41 | 854 / 901 |
uterus | 100% | 2047.54 | 170 / 170 | 92% | 14.77 | 422 / 459 |
intestine | 100% | 2034.63 | 964 / 966 | 92% | 7.48 | 485 / 527 |
stomach | 96% | 1220.68 | 344 / 359 | 93% | 8.49 | 267 / 286 |
breast | 100% | 2074.63 | 459 / 459 | 89% | 7.39 | 994 / 1118 |
bladder | 100% | 1649.95 | 21 / 21 | 88% | 9.14 | 444 / 504 |
skin | 100% | 2167.23 | 1805 / 1809 | 85% | 7.03 | 399 / 472 |
ovary | 98% | 1439.79 | 177 / 180 | 86% | 5.98 | 369 / 430 |
prostate | 98% | 1283.67 | 241 / 245 | 84% | 6.07 | 424 / 502 |
adrenal gland | 95% | 1400.40 | 244 / 258 | 77% | 5.84 | 177 / 230 |
pancreas | 72% | 602.16 | 236 / 328 | 96% | 10.77 | 171 / 178 |
liver | 69% | 540.50 | 156 / 226 | 34% | 1.80 | 138 / 406 |
spleen | 100% | 4464.68 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 4.56 | 1 / 1 |
adipose | 100% | 2334.81 | 1203 / 1204 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 8332.38 | 923 / 929 | 0% | 0 | 0 / 0 |
muscle | 99% | 1757.10 | 794 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 98% | 2552.48 | 1313 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 22.98 | 43 / 45 |
heart | 95% | 1426.63 | 817 / 861 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 59% | 5.75 | 17 / 29 |
eye | 0% | 0 | 0 / 0 | 53% | 2.56 | 42 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001525 | Biological process | angiogenesis |
GO_0071333 | Biological process | cellular response to glucose stimulus |
GO_0055064 | Biological process | chloride ion homeostasis |
GO_0006811 | Biological process | monoatomic ion transport |
GO_0006884 | Biological process | cell volume homeostasis |
GO_0055075 | Biological process | potassium ion homeostasis |
GO_0071805 | Biological process | potassium ion transmembrane transport |
GO_0140157 | Biological process | ammonium import across plasma membrane |
GO_1902476 | Biological process | chloride transmembrane transport |
GO_0071477 | Biological process | cellular hypotonic salinity response |
GO_0007268 | Biological process | chemical synaptic transmission |
GO_1990573 | Biological process | potassium ion import across plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0045202 | Cellular component | synapse |
GO_0030424 | Cellular component | axon |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0019901 | Molecular function | protein kinase binding |
GO_0008519 | Molecular function | ammonium channel activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0015379 | Molecular function | potassium:chloride symporter activity |
Gene name | SLC12A6 |
Protein name | SLC12A6 protein Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3) Solute carrier family 12 (Potassium/chloride transporters), member 6, isoform CRA_c (Solute carrier family 12 member 6) Solute carrier family 12 (Potassium/chloride transporters), member 6 Solute carrier family 12 member 6 |
Synonyms | KCC3 hCG_1998565 |
Description | FUNCTION: [Isoform 1]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells . .; FUNCTION: [Isoform 2]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells (Probable). .; FUNCTION: [Isoform 3]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells (Probable). .; FUNCTION: [Isoform 4]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells (Probable). .; FUNCTION: [Isoform 5]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells (Probable). .; FUNCTION: [Isoform 6]: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells (Probable). . |
Accessions | Q6NSI7 Q9UHW9 ENST00000559523.5 ENST00000397702.6 [Q9UHW9-5] A7E2U9 H0YKJ2 H0YKL8 ENST00000290209.9 [Q9UHW9-2] ENST00000676379.1 ENST00000559236.5 ENST00000560164.5 ENST00000561120.5 H0YMQ9 H0YKE6 ENST00000558589.5 [Q9UHW9-4] Q3ZCQ6 ENST00000561080.5 ENST00000458406.6 [Q9UHW9-5] ENST00000559664.5 ENST00000354181.8 [Q9UHW9-1] ENST00000397707.6 [Q9UHW9-3] ENST00000558667.5 [Q9UHW9-1] B3KXX3 ENST00000560611.5 [Q9UHW9-1] ENST00000559484.1 H0YKQ8 A0A6Q8PH21 |