SENP5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0016925Biological processprotein sumoylation
GO_0016926Biological processprotein desumoylation
GO_0051301Biological processcell division
GO_0006508Biological processproteolysis
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0005634Cellular componentnucleus
GO_0016929Molecular functiondeSUMOylase activity
GO_0070139Molecular functionSUMO-specific endopeptidase activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSENP5
Protein nameSUMO specific peptidase 5
SUMO specific peptidase 5 (SUMO1/sentrin specific peptidase 5, isoform CRA_a)
Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5)
SynonymsFKSG45
hCG_41193
DescriptionFUNCTION: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. .

AccessionsENST00000323460.10 [Q96HI0-1]
Q96HI0
ENST00000434433.1
ENST00000448068.5
H7C2F8
C9JHT8
H7C424
ENST00000445299.6 [Q96HI0-2]
ENST00000419026.5