Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 19 studies | 27% ± 10% | |
astrocyte | 11 studies | 28% ± 12% | |
microglial cell | 10 studies | 24% ± 9% | |
oligodendrocyte | 10 studies | 27% ± 9% | |
glutamatergic neuron | 9 studies | 43% ± 25% | |
oligodendrocyte precursor cell | 9 studies | 26% ± 11% | |
adipocyte | 9 studies | 28% ± 7% | |
GABAergic neuron | 8 studies | 40% ± 22% | |
macrophage | 8 studies | 26% ± 10% | |
fibroblast | 7 studies | 25% ± 7% | |
interneuron | 6 studies | 38% ± 24% | |
myeloid cell | 6 studies | 21% ± 6% | |
epithelial cell | 6 studies | 32% ± 13% | |
dendritic cell | 6 studies | 22% ± 6% | |
type I pneumocyte | 6 studies | 22% ± 6% | |
smooth muscle cell | 6 studies | 22% ± 5% | |
neuron | 5 studies | 31% ± 11% | |
ciliated cell | 5 studies | 21% ± 4% | |
endothelial cell of lymphatic vessel | 5 studies | 31% ± 9% | |
club cell | 5 studies | 21% ± 6% | |
pericyte | 5 studies | 24% ± 8% | |
type II pneumocyte | 5 studies | 21% ± 4% | |
basal cell | 5 studies | 27% ± 12% | |
natural killer cell | 4 studies | 19% ± 2% | |
retinal cone cell | 4 studies | 25% ± 5% | |
mast cell | 4 studies | 20% ± 4% | |
lymphocyte | 4 studies | 24% ± 8% | |
monocyte | 4 studies | 27% ± 3% | |
CD16-positive, CD56-dim natural killer cell, human | 3 studies | 16% ± 0% | |
GABAergic interneuron | 3 studies | 25% ± 4% | |
glial cell | 3 studies | 18% ± 1% | |
B cell | 3 studies | 19% ± 2% | |
amacrine cell | 3 studies | 24% ± 5% | |
retina horizontal cell | 3 studies | 18% ± 4% | |
hepatocyte | 3 studies | 36% ± 25% | |
abnormal cell | 3 studies | 27% ± 15% | |
T cell | 3 studies | 19% ± 1% | |
alveolar macrophage | 3 studies | 27% ± 7% | |
goblet cell | 3 studies | 40% ± 28% | |
transit amplifying cell | 3 studies | 30% ± 19% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 2627.14 | 21 / 21 | 100% | 19.62 | 504 / 504 |
breast | 100% | 2340.64 | 459 / 459 | 100% | 22.05 | 1118 / 1118 |
esophagus | 100% | 2576.13 | 1445 / 1445 | 100% | 26.94 | 183 / 183 |
lung | 100% | 2829.13 | 578 / 578 | 100% | 26.30 | 1155 / 1155 |
ovary | 100% | 2841.32 | 180 / 180 | 100% | 17.79 | 430 / 430 |
uterus | 100% | 2964.75 | 170 / 170 | 100% | 26.74 | 459 / 459 |
brain | 100% | 2914.27 | 2641 / 2642 | 100% | 20.16 | 705 / 705 |
intestine | 100% | 2688.27 | 966 / 966 | 100% | 15.31 | 526 / 527 |
prostate | 100% | 2932.78 | 245 / 245 | 100% | 14.16 | 501 / 502 |
thymus | 100% | 2674.40 | 653 / 653 | 100% | 14.90 | 602 / 605 |
stomach | 100% | 1929.50 | 359 / 359 | 99% | 15.80 | 284 / 286 |
liver | 100% | 1321.43 | 226 / 226 | 99% | 10.20 | 401 / 406 |
pancreas | 100% | 1320.72 | 327 / 328 | 99% | 16.77 | 176 / 178 |
kidney | 100% | 1931.19 | 89 / 89 | 99% | 13.83 | 888 / 901 |
skin | 100% | 2529.84 | 1809 / 1809 | 98% | 21.19 | 464 / 472 |
adrenal gland | 100% | 1959.61 | 258 / 258 | 98% | 16.17 | 226 / 230 |
adipose | 100% | 2388.66 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2434.61 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 21.99 | 29 / 29 |
muscle | 100% | 1835.46 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 3170.61 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 32.44 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.02 | 1 / 1 |
heart | 99% | 1573.85 | 854 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 1719.87 | 876 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 68% | 5.84 | 54 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0016925 | Biological process | protein sumoylation |
GO_0016926 | Biological process | protein desumoylation |
GO_0051301 | Biological process | cell division |
GO_0006508 | Biological process | proteolysis |
GO_0005730 | Cellular component | nucleolus |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0016929 | Molecular function | deSUMOylase activity |
GO_0070139 | Molecular function | SUMO-specific endopeptidase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SENP5 |
Protein name | SUMO specific peptidase 5 SUMO specific peptidase 5 (SUMO1/sentrin specific peptidase 5, isoform CRA_a) Sentrin-specific protease 5 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP5) |
Synonyms | FKSG45 hCG_41193 |
Description | FUNCTION: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. . |
Accessions | ENST00000323460.10 [Q96HI0-1] Q96HI0 ENST00000434433.1 ENST00000448068.5 H7C2F8 C9JHT8 H7C424 ENST00000445299.6 [Q96HI0-2] ENST00000419026.5 |