Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| plasmacytoid dendritic cell | 14 studies | 31% ± 10% | |
| oligodendrocyte precursor cell | 12 studies | 36% ± 19% | |
| macrophage | 8 studies | 38% ± 19% | |
| endothelial cell of lymphatic vessel | 7 studies | 22% ± 7% | |
| glutamatergic neuron | 7 studies | 36% ± 14% | |
| GABAergic neuron | 6 studies | 41% ± 13% | |
| neuron | 6 studies | 36% ± 9% | |
| myeloid cell | 4 studies | 25% ± 7% | |
| type II pneumocyte | 4 studies | 19% ± 4% | |
| interneuron | 4 studies | 37% ± 17% | |
| endothelial cell | 3 studies | 41% ± 17% | |
| glial cell | 3 studies | 31% ± 11% | |
| ionocyte | 3 studies | 22% ± 4% | |
| retinal ganglion cell | 3 studies | 41% ± 10% | |
| Schwann cell | 3 studies | 37% ± 22% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 6 studies | 30% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 98% | 548.71 | 323 / 328 | 66% | 1.66 | 118 / 178 |
| lung | 93% | 403.79 | 540 / 578 | 60% | 3.56 | 696 / 1155 |
| kidney | 88% | 325.44 | 78 / 89 | 49% | 2.34 | 438 / 901 |
| liver | 97% | 752.60 | 220 / 226 | 38% | 1.27 | 153 / 406 |
| intestine | 99% | 1218.00 | 960 / 966 | 10% | 0.24 | 55 / 527 |
| esophagus | 65% | 310.78 | 939 / 1445 | 36% | 3.49 | 65 / 183 |
| spleen | 100% | 1433.96 | 241 / 241 | 0% | 0 | 0 / 0 |
| brain | 73% | 489.87 | 1920 / 2642 | 19% | 0.68 | 133 / 705 |
| bladder | 71% | 137.00 | 15 / 21 | 17% | 0.58 | 88 / 504 |
| adipose | 86% | 373.26 | 1037 / 1204 | 0% | 0 | 0 / 0 |
| thymus | 65% | 146.62 | 426 / 653 | 18% | 0.52 | 110 / 605 |
| adrenal gland | 21% | 72.03 | 54 / 258 | 62% | 6.36 | 142 / 230 |
| skin | 57% | 238.60 | 1034 / 1809 | 20% | 1.10 | 94 / 472 |
| breast | 57% | 167.41 | 262 / 459 | 2% | 0.05 | 26 / 1118 |
| ovary | 31% | 70.50 | 56 / 180 | 24% | 0.55 | 102 / 430 |
| prostate | 51% | 134.22 | 126 / 245 | 3% | 0.06 | 15 / 502 |
| stomach | 41% | 167.05 | 148 / 359 | 12% | 0.29 | 34 / 286 |
| blood vessel | 50% | 143.56 | 671 / 1335 | 0% | 0 | 0 / 0 |
| uterus | 19% | 40.42 | 32 / 170 | 17% | 0.56 | 78 / 459 |
| heart | 32% | 69.36 | 274 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 15% | 30.42 | 143 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 9% | 0.38 | 4 / 45 |
| muscle | 2% | 4.63 | 17 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0019233 | Biological process | sensory perception of pain |
| GO_0048266 | Biological process | behavioral response to pain |
| GO_0009636 | Biological process | response to toxic substance |
| GO_0050974 | Biological process | detection of mechanical stimulus involved in sensory perception |
| GO_0006954 | Biological process | inflammatory response |
| GO_0050965 | Biological process | detection of temperature stimulus involved in sensory perception of pain |
| GO_0086002 | Biological process | cardiac muscle cell action potential involved in contraction |
| GO_0009791 | Biological process | post-embryonic development |
| GO_0006814 | Biological process | sodium ion transport |
| GO_0035725 | Biological process | sodium ion transmembrane transport |
| GO_0007623 | Biological process | circadian rhythm |
| GO_0001518 | Cellular component | voltage-gated sodium channel complex |
| GO_0030424 | Cellular component | axon |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005248 | Molecular function | voltage-gated sodium channel activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SCN9A |
| Protein name | Sodium voltage-gated channel alpha subunit 9 Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) Uncharacterized protein SCN9A Voltage-gated sodium channel subunit alpha NaV1.7 |
| Synonyms | NENA |
| Description | FUNCTION: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient . It is a tetrodotoxin-sensitive Na(+) channel isoform . Plays a role in pain mechanisms, especially in the development of inflammatory pain . . |
| Accessions | A0A0C4DG82 ENST00000667201.2 ENST00000643319.1 ENST00000645283.1 ENST00000303354.11 [Q15858-1] A0A590UJB2 F5C0A4 H7C064 Q53QP0 ENST00000667991.1 ENST00000642356.2 [Q15858-1] A0A2R8YCX9 ENST00000452182.2 A0A590UK23 ENST00000409672.5 [Q15858-3] A0A2R8Y7G0 ENST00000645907.1 [Q15858-4] ENST00000454569.6 Q15858 |