Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 16 studies | 22% ± 9% | |
| capillary endothelial cell | 6 studies | 20% ± 6% | |
| endothelial cell of lymphatic vessel | 6 studies | 21% ± 4% | |
| vein endothelial cell | 5 studies | 18% ± 4% | |
| endothelial cell of vascular tree | 4 studies | 18% ± 2% | |
| glomerular endothelial cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of SCARF1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 5069.94 | 653 / 653 | 99% | 19.07 | 599 / 605 |
| lung | 100% | 4051.27 | 578 / 578 | 97% | 9.37 | 1122 / 1155 |
| breast | 100% | 3187.00 | 459 / 459 | 96% | 6.52 | 1075 / 1118 |
| kidney | 100% | 1674.11 | 89 / 89 | 96% | 16.41 | 866 / 901 |
| adrenal gland | 100% | 1194.26 | 258 / 258 | 95% | 8.77 | 219 / 230 |
| liver | 99% | 1074.47 | 223 / 226 | 92% | 5.31 | 374 / 406 |
| bladder | 100% | 1474.62 | 21 / 21 | 90% | 5.81 | 455 / 504 |
| prostate | 100% | 1255.71 | 244 / 245 | 89% | 4.31 | 449 / 502 |
| intestine | 98% | 1181.84 | 949 / 966 | 90% | 5.04 | 476 / 527 |
| uterus | 99% | 1737.31 | 169 / 170 | 86% | 4.58 | 397 / 459 |
| stomach | 92% | 834.01 | 332 / 359 | 93% | 5.86 | 266 / 286 |
| brain | 83% | 660.48 | 2189 / 2642 | 100% | 8.21 | 703 / 705 |
| esophagus | 91% | 975.50 | 1309 / 1445 | 92% | 5.19 | 168 / 183 |
| pancreas | 56% | 335.12 | 183 / 328 | 98% | 8.29 | 174 / 178 |
| skin | 64% | 545.04 | 1158 / 1809 | 83% | 5.01 | 394 / 472 |
| ovary | 66% | 543.97 | 119 / 180 | 81% | 3.67 | 349 / 430 |
| adipose | 100% | 3584.25 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| spleen | 100% | 6978.34 | 241 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 2.70 | 1 / 1 |
| heart | 100% | 1436.83 | 858 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 97% | 10.46 | 28 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 4.82 | 40 / 45 |
| muscle | 88% | 770.98 | 705 / 803 | 0% | 0 | 0 / 0 |
| blood vessel | 79% | 810.35 | 1050 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 73% | 1435.40 | 681 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 55% | 2.65 | 44 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0016358 | Biological process | dendrite development |
| GO_0016322 | Biological process | neuron remodeling |
| GO_0007157 | Biological process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
| GO_0010976 | Biological process | positive regulation of neuron projection development |
| GO_0006898 | Biological process | receptor-mediated endocytosis |
| GO_0048680 | Biological process | positive regulation of axon regeneration |
| GO_0006707 | Biological process | cholesterol catabolic process |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0016020 | Cellular component | membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0030169 | Molecular function | low-density lipoprotein particle binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0005044 | Molecular function | scavenger receptor activity |
| Gene name | SCARF1 |
| Protein name | Scavenger receptor class F member 1 Alternative protein SCARF1 Scavenger receptor class F member 1 (Acetyl LDL receptor) (Scavenger receptor expressed by endothelial cells 1) (SREC-I) |
| Synonyms | SREC KIAA0149 |
| Description | FUNCTION: Mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). Mediates heterophilic interactions, suggesting a function as adhesion protein. Plays a role in the regulation of neurite-like outgrowth (By similarity). . |
| Accessions | L8EAP7 I3L4R9 ENST00000571272.5 [Q14162-3] ENST00000573852.5 A0A0A0MR54 Q14162 ENST00000631462.1 [Q14162-5] ENST00000633740.1 ENST00000632317.1 [Q14162-3] ENST00000616905.1 ENST00000434376.6 [Q14162-5] ENST00000621348.4 [Q14162-1] ENST00000263071.9 [Q14162-1] |