SAR1B report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0002474Biological processantigen processing and presentation of peptide antigen via MHC class I
GO_1990253Biological processcellular response to leucine starvation
GO_0090110Biological processCOPII-coated vesicle cargo loading
GO_0003400Biological processregulation of COPII vesicle coating
GO_1903432Biological processregulation of TORC1 signaling
GO_0006886Biological processintracellular protein transport
GO_0061024Biological processmembrane organization
GO_0070863Biological processpositive regulation of protein exit from endoplasmic reticulum
GO_0016050Biological processvesicle organization
GO_0032368Biological processregulation of lipid transport
GO_0042953Biological processlipoprotein transport
GO_0055088Biological processlipid homeostasis
GO_0006888Biological processendoplasmic reticulum to Golgi vesicle-mediated transport
GO_0140353Biological processlipid export from cell
GO_1904262Biological processnegative regulation of TORC1 signaling
GO_0048208Biological processCOPII vesicle coating
GO_0005789Cellular componentendoplasmic reticulum membrane
GO_0030127Cellular componentCOPII vesicle coat
GO_0070971Cellular componentendoplasmic reticulum exit site
GO_0005829Cellular componentcytosol
GO_0012507Cellular componentER to Golgi transport vesicle membrane
GO_0032580Cellular componentGolgi cisterna membrane
GO_0005765Cellular componentlysosomal membrane
GO_0003925Molecular functionG protein activity
GO_0005525Molecular functionGTP binding
GO_0140785Molecular functionamino acid sensor activity
GO_0046872Molecular functionmetal ion binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameSAR1B
Protein nameSecretion associated Ras related GTPase 1B
GTP-binding protein SAR1b (GTP-binding protein B) (GTBPB)
Secretion associated Ras related GTPase 1B (cDNA FLJ32259 fis, clone PROST1000298, highly similar to GTP-binding protein SAR1b)
GTP-binding protein SAR1b
SynonymsSARA2
DKFZp434B2017
SARB
DescriptionFUNCTION: GTP-binding protein involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Activated by the guanine nucleotide exchange factor PREB (By similarity). Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). Synergizes with the cargo receptor SURF4 to mediate the export of lipoproteins from the endoplasmic reticulum, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis . .

AccessionsD6RAA2
ENST00000505758.5
ENST00000439578.5
ENST00000507419.5
D6R9R5
Q9Y6B6
ENST00000509730.5
Q9H029
D6RDB2
ENST00000503318.5
ENST00000509937.5
ENST00000502286.1
D6RD69
ENST00000502539.5
ENST00000402673.7