RIN2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0010595Biological processpositive regulation of endothelial cell migration
GO_2001214Biological processpositive regulation of vasculogenesis
GO_1904906Biological processpositive regulation of endothelial cell-matrix adhesion via fibronectin
GO_0006897Biological processendocytosis
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0005575Cellular componentcellular_component
GO_0005829Cellular componentcytosol
GO_0030139Cellular componentendocytic vesicle
GO_0030695Molecular functionGTPase regulator activity
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0031267Molecular functionsmall GTPase binding
GO_0005096Molecular functionGTPase activator activity

IV. Literature review

[source]
Gene nameRIN2
Protein nameRas and Rab interactor 2 (Ras association domain family 4) (Ras inhibitor JC265) (Ras interaction/interference protein 2)
RIN2 protein
Ras and Rab interactor 2
SynonymsRASSF4
DescriptionFUNCTION: Ras effector protein. May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway. May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP. .

AccessionsA1A4T0
Q8WYP3
ENST00000648440.1 [Q8WYP3-1]
E7EPJ1
ENST00000440354.2
ENST00000255006.12 [Q8WYP3-1]