Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 9 studies | 28% ± 13% | |
glutamatergic neuron | 8 studies | 45% ± 26% | |
oligodendrocyte precursor cell | 8 studies | 25% ± 9% | |
adipocyte | 7 studies | 21% ± 4% | |
GABAergic neuron | 7 studies | 44% ± 22% | |
endothelial cell | 6 studies | 27% ± 13% | |
interneuron | 6 studies | 35% ± 14% | |
neuron | 5 studies | 26% ± 10% | |
oligodendrocyte | 5 studies | 25% ± 8% | |
GABAergic interneuron | 3 studies | 26% ± 6% | |
granule cell | 3 studies | 23% ± 2% | |
microglial cell | 3 studies | 23% ± 5% | |
cardiac muscle cell | 3 studies | 20% ± 3% | |
ciliated cell | 3 studies | 19% ± 5% | |
epithelial cell | 3 studies | 20% ± 2% | |
retinal rod cell | 3 studies | 25% ± 1% | |
ependymal cell | 3 studies | 44% ± 14% | |
endothelial cell of lymphatic vessel | 3 studies | 18% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 1362.05 | 245 / 245 | 100% | 7.61 | 501 / 502 |
brain | 100% | 2186.92 | 2640 / 2642 | 100% | 12.89 | 703 / 705 |
thymus | 100% | 2389.58 | 653 / 653 | 99% | 9.71 | 601 / 605 |
breast | 100% | 1360.19 | 459 / 459 | 99% | 9.47 | 1109 / 1118 |
ovary | 100% | 1426.82 | 180 / 180 | 99% | 7.47 | 426 / 430 |
pancreas | 99% | 944.37 | 326 / 328 | 99% | 6.39 | 176 / 178 |
adrenal gland | 100% | 1269.67 | 258 / 258 | 98% | 8.91 | 226 / 230 |
intestine | 100% | 1398.11 | 966 / 966 | 98% | 6.00 | 517 / 527 |
uterus | 100% | 1814.04 | 170 / 170 | 98% | 6.29 | 450 / 459 |
kidney | 100% | 1215.56 | 89 / 89 | 98% | 7.99 | 883 / 901 |
bladder | 100% | 1401.05 | 21 / 21 | 98% | 5.62 | 492 / 504 |
stomach | 98% | 854.09 | 353 / 359 | 98% | 6.10 | 281 / 286 |
esophagus | 97% | 1008.11 | 1403 / 1445 | 98% | 6.52 | 180 / 183 |
lung | 97% | 863.01 | 558 / 578 | 99% | 5.71 | 1142 / 1155 |
skin | 99% | 812.13 | 1787 / 1809 | 96% | 8.05 | 454 / 472 |
liver | 100% | 848.74 | 226 / 226 | 89% | 6.12 | 362 / 406 |
adipose | 100% | 1354.67 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1556.92 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1312.30 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 5.76 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.61 | 1 / 1 |
muscle | 100% | 933.13 | 800 / 803 | 0% | 0 | 0 / 0 |
heart | 98% | 1135.75 | 844 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 90% | 4.97 | 72 / 80 |
lymph node | 0% | 0 | 0 / 0 | 55% | 1.95 | 16 / 29 |
peripheral blood | 39% | 280.24 | 366 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0008277 | Biological process | regulation of G protein-coupled receptor signaling pathway |
GO_0005813 | Cellular component | centrosome |
GO_0005829 | Cellular component | cytosol |
GO_0005938 | Cellular component | cell cortex |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0001965 | Molecular function | G-protein alpha-subunit binding |
Gene name | RIC8B |
Protein name | RIC8 guanine nucleotide exchange factor B Synembryn (Protein Ric-8) Synembryn-B (Brain synembryn) (hSyn) (Protein Ric-8B) |
Synonyms | |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. Able to potentiate G(olf)-alpha-dependent cAMP accumulation suggesting that it may be an important component for odorant signal transduction. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . |
Accessions | F8VSN5 F8VR30 Q9NVN3 ENST00000552619.1 B7WPL0 ENST00000392837.9 ENST00000550215.5 ENST00000392839.6 [Q9NVN3-5] J3QRA4 F8VY51 ENST00000549643.5 ENST00000546449.2 ENST00000548914.5 ENST00000355478.6 [Q9NVN3-3] ENST00000470960.1 [Q9NVN3-4] H0YHS3 ENST00000462949.5 [Q9NVN3-1] |