Name | Number of supported studies | Average coverage | |
---|---|---|---|
CD16-positive, CD56-dim natural killer cell, human | 7 studies | 17% ± 2% | |
natural killer cell | 6 studies | 19% ± 2% | |
CD16-negative, CD56-bright natural killer cell, human | 5 studies | 18% ± 2% | |
epithelial cell | 5 studies | 28% ± 12% | |
gamma-delta T cell | 5 studies | 19% ± 5% | |
CD8-positive, alpha-beta T cell | 4 studies | 18% ± 3% | |
mucosal invariant T cell | 4 studies | 17% ± 0% | |
fibroblast | 4 studies | 22% ± 6% | |
endothelial cell | 4 studies | 23% ± 9% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 19% ± 4% | |
non-classical monocyte | 3 studies | 22% ± 5% | |
dendritic cell | 3 studies | 24% ± 7% | |
CD8-positive, alpha-beta memory T cell | 3 studies | 18% ± 2% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 3 studies | 20% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 5280.00 | 1445 / 1445 | 100% | 42.41 | 183 / 183 |
prostate | 100% | 5043.76 | 245 / 245 | 100% | 52.97 | 502 / 502 |
skin | 100% | 5971.70 | 1809 / 1809 | 100% | 59.65 | 472 / 472 |
stomach | 100% | 3692.23 | 359 / 359 | 100% | 43.04 | 286 / 286 |
uterus | 100% | 5115.35 | 170 / 170 | 100% | 52.85 | 459 / 459 |
lung | 100% | 4855.46 | 578 / 578 | 100% | 51.22 | 1154 / 1155 |
breast | 100% | 4757.87 | 459 / 459 | 100% | 64.35 | 1116 / 1118 |
brain | 100% | 3573.83 | 2637 / 2642 | 100% | 61.27 | 705 / 705 |
ovary | 100% | 4364.29 | 180 / 180 | 100% | 43.91 | 429 / 430 |
pancreas | 100% | 2625.99 | 327 / 328 | 100% | 48.53 | 178 / 178 |
thymus | 100% | 4427.04 | 653 / 653 | 100% | 49.78 | 603 / 605 |
kidney | 100% | 3948.69 | 89 / 89 | 100% | 45.56 | 897 / 901 |
intestine | 100% | 5023.68 | 966 / 966 | 99% | 45.81 | 524 / 527 |
bladder | 100% | 5507.29 | 21 / 21 | 99% | 49.18 | 500 / 504 |
liver | 100% | 2500.30 | 226 / 226 | 99% | 33.25 | 402 / 406 |
adrenal gland | 100% | 4715.72 | 258 / 258 | 98% | 36.84 | 226 / 230 |
adipose | 100% | 4667.68 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 5006.83 | 1335 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 100% | 46.22 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 55.37 | 29 / 29 |
spleen | 100% | 5023.64 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 35.13 | 1 / 1 |
muscle | 99% | 2262.94 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 99% | 3209.52 | 855 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 51.30 | 44 / 45 |
peripheral blood | 98% | 4329.47 | 907 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0071711 | Biological process | basement membrane organization |
GO_0001944 | Biological process | vasculature development |
GO_0070586 | Biological process | cell-cell adhesion involved in gastrulation |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0007193 | Biological process | adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway |
GO_0001701 | Biological process | in utero embryonic development |
GO_0042074 | Biological process | cell migration involved in gastrulation |
GO_0008542 | Biological process | visual learning |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0001965 | Molecular function | G-protein alpha-subunit binding |
GO_0005515 | Molecular function | protein binding |
Gene name | RIC8A |
Protein name | RIC8 guanine nucleotide exchange factor A Synembryn (Protein Ric-8) Synembryn-A (Protein Ric-8A) |
Synonyms | |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). Also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . FUNCTION: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP. . |
Accessions | H0YEN0 E9PSI0 ENST00000530889.1 E9PI04 ENST00000524854.5 E9PLE5 ENST00000529275.1 H0YC88 Q9NPQ8 ENST00000527728.1 ENST00000528357.5 ENST00000325207.9 [Q9NPQ8-3] E9PMP0 H0YE35 ENST00000626818.1 ENST00000527696.5 [Q9NPQ8-2] ENST00000526104.6 [Q9NPQ8-1] ENST00000526982.1 ENST00000527468.1 |