RGS8 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of RGS8 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	96%	1997.52	2528 / 2642	61%	2.79	433 / 705
thymus	91%	949.85	593 / 653	24%	2.79	145 / 605
adrenal gland	83%	247.64	213 / 258	20%	1.13	46 / 230
ovary	11%	18.74	19 / 180	1%	0.03	5 / 430
lymph node	0%	0	0 / 0	7%	1.81	2 / 29
intestine	4%	5.24	39 / 966	1%	0.02	3 / 527
eye	0%	0	0 / 0	4%	0.54	3 / 80
breast	0%	0	0 / 459	3%	0.09	37 / 1118
skin	0%	0.26	3 / 1809	3%	0.21	13 / 472
kidney	0%	0	0 / 89	3%	0.07	23 / 901
tonsil	0%	0	0 / 0	2%	0.06	1 / 45
adipose	2%	2.33	21 / 1204	0%	0	0 / 0
uterus	0%	0	0 / 170	2%	0.04	8 / 459
lung	0%	0.16	1 / 578	1%	0.03	15 / 1155
pancreas	0%	0.28	1 / 328	1%	0.01	2 / 178
bladder	0%	0	0 / 21	1%	0.05	3 / 504
liver	0%	0	0 / 226	0%	0.01	2 / 406
stomach	0%	0	0 / 359	0%	0.02	1 / 286
muscle	0%	0.18	1 / 803	0%	0	0 / 0
heart	0%	0.11	1 / 861	0%	0	0 / 0
blood vessel	0%	0.08	1 / 1335	0%	0	0 / 0
esophagus	0%	0.16	1 / 1445	0%	0	0 / 183
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0060159	Biological process	regulation of dopamine receptor signaling pathway
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0007213	Biological process	G protein-coupled acetylcholine receptor signaling pathway
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0009968	Biological process	negative regulation of signal transduction
GO_0009898	Cellular component	cytoplasmic side of plasma membrane
GO_0043204	Cellular component	perikaryon
GO_0030425	Cellular component	dendrite
GO_0045202	Cellular component	synapse
GO_0005886	Cellular component	plasma membrane
GO_0032809	Cellular component	neuronal cell body membrane
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding
GO_0005096	Molecular function	GTPase activator activity
GO_0003924	Molecular function	GTPase activity

Gene name	RGS8
Protein name	Regulator of G protein signaling 8 Regulator of G-protein signaling 8 (RGS8)
Synonyms
Description	FUNCTION: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form . Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity). .
Accessions	D6RD36 ENST00000258302.8 [P57771-2] ENST00000367557.8 [P57771-1] P57771 ENST00000483095.6 [P57771-1] ENST00000515211.2 [P57771-1] ENST00000508450.5 ENST00000367556.5 [P57771-1]

RGS8 report