RGS16 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007601Biological processvisual perception
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0043547Biological processpositive regulation of GTPase activity
GO_0009968Biological processnegative regulation of signal transduction
GO_0005886Cellular componentplasma membrane
GO_0016020Cellular componentmembrane
GO_0005737Cellular componentcytoplasm
GO_0005096Molecular functionGTPase activator activity
GO_0005516Molecular functioncalmodulin binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRGS16
Protein nameRegulator of G-protein signaling 16 (RGS16) (A28-RGS14P) (Retinal-specific RGS) (RGS-r) (hRGS-r) (Retinally abundant regulator of G-protein signaling)
SynonymsRGSR
DescriptionFUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form . Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity). .

AccessionsO15492
ENST00000367558.6