RGS12 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0008277Biological processregulation of G protein-coupled receptor signaling pathway
GO_0009968Biological processnegative regulation of signal transduction
GO_0016363Cellular componentnuclear matrix
GO_0005730Cellular componentnucleolus
GO_0000794Cellular componentcondensed nuclear chromosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0030425Cellular componentdendrite
GO_0045202Cellular componentsynapse
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0030695Molecular functionGTPase regulator activity
GO_0005096Molecular functionGTPase activator activity
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRGS12
Protein nameRGS12 protein
Regulator of G-protein signalling 12
Regulator of G-protein signaling 12 (RGS12)
RGS12TS isoform 2 (Regulator of G-protein signalling 12, isoform CRA_g)
Regulator of G protein signaling 12
SynonymshCG_16460
DescriptionFUNCTION: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. .; FUNCTION: [Isoform 5]: Behaves as a cell cycle-dependent transcriptional repressor, promoting inhibition of S-phase DNA synthesis. .

AccessionsQ506M0
ENST00000514268.5
Q3B858
Q56A82
ENST00000338806.4 [O14924-3]
ENST00000382788.7 [O14924-4]
Q8WX96
ENST00000643191.1
E9PBG5
ENST00000344733.9 [O14924-1]
O14924
A0A2R8YCJ1
ENST00000336727.8 [O14924-1]