REV1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0070987Biological processerror-free translesion synthesis
GO_0009411Biological processresponse to UV
GO_0006260Biological processDNA replication
GO_0042276Biological processerror-prone translesion synthesis
GO_0005654Cellular componentnucleoplasm
GO_0017125Molecular functiondeoxycytidyl transferase activity
GO_0003887Molecular functionDNA-directed DNA polymerase activity
GO_0005515Molecular functionprotein binding
GO_0003684Molecular functiondamaged DNA binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameREV1
Protein nameDNA repair protein REV1 (EC 2.7.7.-)
REV1 DNA directed polymerase
DNA repair protein REV1 (EC 2.7.7.-) (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase)
SynonymsREV1L
DescriptionFUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. .

FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. .

FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents. .

AccessionsF8WCR0
ENST00000438366.1
ENST00000413697.5
Q9UBZ9
ENST00000393445.7 [Q9UBZ9-2]
C9JPS2
ENST00000450415.1
Q49AI5
H7C263
ENST00000258428.8 [Q9UBZ9-1]
A1L461