RASSF7 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0006915Biological processapoptotic process
GO_0034451Cellular componentcentriolar satellite
GO_0005737Cellular componentcytoplasm
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRASSF7
Protein nameRas association domain-containing protein 7 (HRAS1-related cluster protein 1)
Ras association domain family member 7 (Ras association domain-containing protein 7)
Ras association domain-containing protein 7
Ras association domain family member 7
SynonymsHRC1
C11orf13
DescriptionFUNCTION: Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. .

AccessionsENST00000631421.1
ENST00000633903.1
ENST00000531112.1
A0A0J9YYE4
A0A0G2JLR5
ENST00000528736.1
ENST00000620201.4
ENST00000622905.2
ENST00000454668.2 [Q02833-3]
F8W7Q0
ENST00000397582.7 [Q02833-2]
ENST00000622100.4
E9PM39
ENST00000431809.5 [Q02833-2]
Q02833
ENST00000414138.6
ENST00000397583.8 [Q02833-1]
ENST00000632673.1
A0A0G2JMW4
ENST00000632833.1
H0YEI0