Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 9 studies | 23% ± 5% | |
oligodendrocyte | 8 studies | 59% ± 14% | |
GABAergic neuron | 7 studies | 49% ± 25% | |
glutamatergic neuron | 7 studies | 59% ± 22% | |
oligodendrocyte precursor cell | 7 studies | 41% ± 16% | |
CD4-positive, alpha-beta T cell | 7 studies | 26% ± 9% | |
microglial cell | 7 studies | 53% ± 11% | |
astrocyte | 7 studies | 37% ± 14% | |
macrophage | 5 studies | 24% ± 8% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 4 studies | 19% ± 2% | |
mucosal invariant T cell | 4 studies | 20% ± 3% | |
regulatory T cell | 4 studies | 30% ± 8% | |
amacrine cell | 4 studies | 36% ± 7% | |
retina horizontal cell | 4 studies | 27% ± 10% | |
retinal cone cell | 4 studies | 27% ± 9% | |
smooth muscle cell | 4 studies | 30% ± 9% | |
interneuron | 4 studies | 62% ± 14% | |
CD8-positive, alpha-beta T cell | 3 studies | 26% ± 7% | |
epithelial cell | 3 studies | 28% ± 11% | |
GABAergic amacrine cell | 3 studies | 44% ± 13% | |
Mueller cell | 3 studies | 30% ± 7% | |
glycinergic amacrine cell | 3 studies | 32% ± 5% | |
retinal ganglion cell | 3 studies | 45% ± 23% | |
retinal rod cell | 3 studies | 20% ± 0% | |
myeloid cell | 3 studies | 33% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 1674.19 | 459 / 459 | 100% | 4.47 | 1114 / 1118 |
prostate | 100% | 1330.26 | 245 / 245 | 100% | 3.97 | 500 / 502 |
esophagus | 100% | 1317.37 | 1444 / 1445 | 99% | 3.36 | 182 / 183 |
brain | 99% | 2182.09 | 2615 / 2642 | 100% | 3.67 | 705 / 705 |
adrenal gland | 100% | 1149.24 | 258 / 258 | 99% | 3.67 | 227 / 230 |
lung | 100% | 1788.09 | 577 / 578 | 99% | 3.00 | 1141 / 1155 |
thymus | 100% | 1321.55 | 653 / 653 | 99% | 3.27 | 596 / 605 |
uterus | 100% | 1471.20 | 170 / 170 | 98% | 3.13 | 451 / 459 |
bladder | 100% | 1551.43 | 21 / 21 | 97% | 2.62 | 490 / 504 |
ovary | 100% | 1525.03 | 180 / 180 | 97% | 2.18 | 418 / 430 |
intestine | 100% | 1334.01 | 966 / 966 | 95% | 2.77 | 502 / 527 |
stomach | 100% | 852.74 | 358 / 359 | 95% | 2.85 | 273 / 286 |
kidney | 99% | 786.19 | 88 / 89 | 96% | 3.24 | 865 / 901 |
pancreas | 98% | 632.70 | 320 / 328 | 97% | 2.58 | 173 / 178 |
skin | 100% | 1704.20 | 1808 / 1809 | 90% | 3.09 | 426 / 472 |
liver | 97% | 554.70 | 219 / 226 | 90% | 2.00 | 366 / 406 |
adipose | 100% | 1471.24 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1634.42 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 5.23 | 29 / 29 |
spleen | 100% | 1589.35 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 2.99 | 45 / 45 |
muscle | 99% | 821.23 | 791 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 95% | 1805.07 | 879 / 929 | 0% | 0 | 0 / 0 |
heart | 94% | 757.24 | 806 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 61% | 1.66 | 49 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030033 | Biological process | microvillus assembly |
GO_0090557 | Biological process | establishment of endothelial intestinal barrier |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0072659 | Biological process | protein localization to plasma membrane |
GO_0043087 | Biological process | regulation of GTPase activity |
GO_0043547 | Biological process | positive regulation of GTPase activity |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005813 | Cellular component | centrosome |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0030139 | Cellular component | endocytic vesicle |
GO_0005085 | Molecular function | guanyl-nucleotide exchange factor activity |
GO_0070300 | Molecular function | phosphatidic acid binding |
GO_0030742 | Molecular function | GTP-dependent protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0031267 | Molecular function | small GTPase binding |
Gene name | RAPGEF6 |
Protein name | HCG1981012, isoform CRA_b (RAPGEF6 protein) Rap guanine nucleotide exchange factor 6 Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2) |
Synonyms | PDZGEF2 hCG_1981012 |
Description | FUNCTION: Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP. . |
Accessions | ENST00000513227.5 D6RD23 B7Z7Y1 D6RB02 ENST00000308008.10 [Q8TEU7-2] ENST00000507093.5 [Q8TEU7-3] ENST00000510071.5 [Q8TEU7-6] ENST00000509018.6 [Q8TEU7-1] D6RIH0 D6RE77 B2RTU6 ENST00000296859.10 [Q8TEU7-4] ENST00000504039.2 ENST00000671916.1 A0A5F9ZHG7 Q8TEU7 ENST00000627212.2 [Q8TEU7-5] ENST00000512052.5 ENST00000504575.5 ENST00000515170.5 |