RAPGEF5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007265Biological processRas protein signal transduction
GO_0007399Biological processnervous system development
GO_0007264Biological processsmall GTPase-mediated signal transduction
GO_0016604Cellular componentnuclear body
GO_0005654Cellular componentnucleoplasm
GO_0005886Cellular componentplasma membrane
GO_0005634Cellular componentnucleus
GO_0005085Molecular functionguanyl-nucleotide exchange factor activity
GO_0030742Molecular functionGTP-dependent protein binding

IV. Literature review

[source]
Gene nameRAPGEF5
Protein nameRap guanine nucleotide exchange factor 5 (Guanine nucleotide exchange factor for Rap1) (M-Ras-regulated Rap GEF) (MR-GEF) (Related to Epac) (Repac)
HCG38228, isoform CRA_b (Rap guanine nucleotide exchange factor 5 isoform 2)
Rap guanine nucleotide exchange factor 5 isoform 1
Rap guanine nucleotide exchange factor 5
SynonymshCG_38228
MRGEF
GFR
KIAA0277
DescriptionFUNCTION: Guanine nucleotide exchange factor (GEF) for RAP1A, RAP2A and MRAS/M-Ras-GTP. Its association with MRAS inhibits Rap1 activation. .

AccessionsA8MQ07
F8WD32
A0A590UJR0
ENST00000665637.1
ENST00000401957.6 [Q92565-1]
E9PGY3
A0A0S2Z5S1
ENST00000420196.5
A0A0S2Z561
C9JHM4
ENST00000451559.1
ENST00000344041.10
ENST00000405243.1
ENST00000458533.5
Q92565
C9JBS6