RAB25 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031268Biological processpseudopodium organization
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0015031Biological processprotein transport
GO_0060627Biological processregulation of vesicle-mediated transport
GO_0003382Biological processepithelial cell morphogenesis
GO_0006887Biological processexocytosis
GO_0010634Biological processpositive regulation of epithelial cell migration
GO_0031143Cellular componentpseudopodium
GO_0031260Cellular componentpseudopodium membrane
GO_0070062Cellular componentextracellular exosome
GO_0005794Cellular componentGolgi apparatus
GO_0005886Cellular componentplasma membrane
GO_0031410Cellular componentcytoplasmic vesicle
GO_0055037Cellular componentrecycling endosome
GO_0031489Molecular functionmyosin V binding
GO_0005525Molecular functionGTP binding
GO_0005515Molecular functionprotein binding
GO_0003924Molecular functionGTPase activity

IV. Literature review

[source]
Gene nameRAB25
Protein nameRas-related protein Rab-25 (CATX-8)
SynonymsCATX8
DescriptionFUNCTION: Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia . Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). .

AccessionsENST00000361084.10
P57735