PTPRF report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_1900121Biological processnegative regulation of receptor binding
GO_0099560Biological processsynaptic membrane adhesion
GO_0007185Biological processcell surface receptor protein tyrosine phosphatase signaling pathway
GO_0035335Biological processpeptidyl-tyrosine dephosphorylation
GO_0007155Biological processcell adhesion
GO_0031102Biological processneuron projection regeneration
GO_0016477Biological processcell migration
GO_0048679Biological processregulation of axon regeneration
GO_0070062Cellular componentextracellular exosome
GO_0043025Cellular componentneuronal cell body
GO_0005886Cellular componentplasma membrane
GO_0043005Cellular componentneuron projection
GO_0044877Molecular functionprotein-containing complex binding
GO_0050839Molecular functioncell adhesion molecule binding
GO_0005001Molecular functiontransmembrane receptor protein tyrosine phosphatase activity
GO_0008201Molecular functionheparin binding
GO_0035373Molecular functionchondroitin sulfate proteoglycan binding
GO_0004725Molecular functionprotein tyrosine phosphatase activity

IV. Literature review

[source]
Gene namePTPRF
Protein nameReceptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48)
Protein tyrosine phosphatase receptor type F
Receptor-type tyrosine-protein phosphatase F
SynonymsLAR
DescriptionFUNCTION: Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; FUNCTION: The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.

AccessionsH0Y380
P10586
ENST00000414879.5
ENST00000412568.6
H0Y4H1
H0Y7Z9
ENST00000429895.5
ENST00000438120.5 [P10586-2]
H0Y6Z7
ENST00000617451.4
G1UI20
A2A437
ENST00000359947.9 [P10586-1]
ENST00000372407.4
ENST00000437607.1